Effects of dietary sodium butyrate on growth, diet conversion, body chemical compositions and distal intestinal health in yellow drum ( Nibea albiflora , Richardson)

Abstract

The present study was conducted to investigate the effects of sodium butyrate (SB) on the physical barrier function, pro‐inflammatory response and possible underlying mechanisms in the distal intestine (DI) of yellow drum when fed a high‐SBM diet. Three iso‐proteic and iso‐lipidic diets were formulated with fish meal (FM, the control), 45% fish meal protein replaced by SBM (SBM) and 45% fish meal protein replaced by SBM but supplemented with 0.15% SB (SBM + SB). Fish were fed twice daily for 10 weeks. Results indicated that SB supplementation significantly increased the specific growth rate (SGR) and feed efficiency ratio (FER) and methionine content of muscle when compared with those of fish fed the SBM diet (p < .05). The morphologic histology results showed that SB dramatically improved the physical barrier structure, characterized as increases of fold height (FH) and muscular thickness (MT) (p < .05). RT‐qPCR data were accordant with morphologic histology results, in which claudin 3, claudin 4 and occludin were increased while claudin 7 and myosin light chain kinase (MLCK) mRNA expression levels were decreased (p < .05). Sodium butyrate also exerted anti‐inflammatory function, which may be attributed to the suppression of nucleus p65 protein expression. Results suggest SB can be incorporated in high‐SBM diets to ameliorate the negative consequences of alternative dietary ingredients on yellow drum physiology.

Effects of dietary tributyrin on growth performance, body composition, serum biochemical indexes and lipid metabolism‐related genes expression of juvenile large yellow croaker ( Larimichthys crocea ) fed with high level soybean oil diets

“…Based on the results, appropriate supplementation of tributyrin (2 g/kg) significantly increased the growth performance of large yellow croaker. The similar effect was also confirmed by research in turbot ( Scophthalmus maximus ) (Liu et al., 2019), yellow drum ( Nibea albiflora ) (Wu et al., 2019), golden pompano ( Trachinotus ovatus ) (Zhou et al., 2019) and sea bream ( Sparus aurata ) (Robles et al., 2013). This growth promotion effect of tributyrin involved multiple mechanisms.…”

β-Conglycinin regulates distal intestinal immunity through the CIITA-mediated MHC II-PI3K/Akt/mTOR signaling pathway in hybrid grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂): The ameliorative effects of sodium butyrate (NaB)

“…However, supplementing the grouper diet with NaB reversed the detrimental effects of high-dose 7, resulting in a reduction in the Id/Ph ratio, and signi cantly enhancing intestinal development. Similar results have also been obtained for the yellow drum (Nibea albi ora, Richardson) (Wu, et al, 2020a).…”

Effects of dietary sodium butyrate on growth, digestive enzymes, body composition and nutrient retention-related gene expression of juvenile yellow catfish (Pelteobagrus fulvidraco)

“…The syntheses of proteins and lipids are key processes involved in growth response ( Mommsen, 2001 ). In gilthead sea bream and yellow drum ( Nibea albiflora ) (Richardson), the improvement of growth performance may be due to the increase in the availability of essential amino acids of fish fed SB diets ( Robles et al, 2013 ; Wu et al, 2019 ). Wu et al (2019) suggested that supplementation of 0.15% SB increased crude lipid content of the whole body in yellow drum.…”