Effects of dietary seaweed, .BETA.-glucan and yeast on immunity and growth traits in growing pigs

Mycoplasma pneumonia of swine (MPS) is responsible for significant economic losses in the swine industry. We selected Landrace pigs for reduced MPS pulmonary lesions over five generations, and measured concentrations of the following cytokines: interleukin (IL)-10, IL-13, IL-17, tumor necrosis factor (TNF)-α and interferon (IFN)-γ to estimate their correlation with MPS lesions. Sheep red blood cells (SRBC) were injected twice intramuscularly at 70 and 95 kg body weight. Blood serum samples were collected after 1 week of secondary SRBC inoculation and cytokine concentrations were analyzed by ELISA. Genetic parameters and breeding values were estimated. The heritability estimates of IL-10, IL-13, IL-17, TNF-α and IFN-γ were 0.20 ± 0.06, 0.12 ± 0.06, 0.27 ± 0.07, 0.20 ± 0.10 and 0.05 ± 0.03, respectively. Genetic correlations of IL-17 and TNF-α with pulmonary MPS lesions were high (-0.86 ± 0.13 and 0.69 ± 0.29, respectively) and those of IFN-γ and IL-13 with MPS lesions were moderately negative (-0.45). Through selection, the breeding values of IL-17 and IFN-γ increased substantially and those of TNF-α decreased. These results suggest that innate and cellular immunity are more important for the suppression of pulmonary lesions in MPS than humoral-mediated immunity, such as antibody response.

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“…The PA was measured as described by Suzuki et al (2009). The PA was measured as described by Suzuki et al (2009).…”

Section: Phenotypic Measurement Of Immune-capacity Traitsmentioning

confidence: 99%

Correlated response of peripheral blood cytokines with selection for reduced mycoplasma pneumonia of swine lesions in Landrace pigs

Sato

Okamura

Kojima-Shibata³

et al. 2015

Animal Science Journal

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“…It has been suggested that seaweeds may have an important role in modulating human chronic disease (Brown et al, 2014) or elevating disease resistance by improving immunity in pigs (Maghin, Ratti, & Carino, 2014). Based on this information, we conducted several experiments with seaweeds, especially A. nodosum, as a feed additive, and found that the addition of A. nodosum increased sheep red blood-specific IgG production in serum in pigs (Katayama et al, 2011;Suzuki et al, 2009). Moreover, Dierick, Ovyn, and Smet (2009) reported that A. nodosum addition to pig feed improved the gut health of the weaned piglets.…”

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confidence: 99%

Addition of Wakame seaweed (Undaria pinnatifida) stalk to animal feed enhances immune response and improves intestinal microflora in pigs

Shimazu

Borjigin

Katoh

et al. 2019

Animal Science Journal

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This study was conducted to evaluate the effects of supplementation of Wakame seaweed stalks on the immunity and intestinal microflora of pigs. Three separate experiments were performed: Relatively young (start at 20–30 kg; Experiments 1 and 2) and fattening period (70 kg; Experiment 3). All pigs (including the control group) were fed the same commercial feed, free from antibiotic additives, but in the feed for the treatment groups, 1% seaweed powder was added. There were no group differences observed in daily weight gain and feed intake in Experiments 1 and 2 between groups; however, daily weight gain was significantly higher in the treatment group compared to the control group in Experiment 3. The percentage of peripheral blood natural killer cells of the treatment group was significantly higher than that of the control group in all experiments. Although addition of seaweed changed the gene expression of cytokine and toll‐like receptors of the small intestinal Peyer's patches slightly, seaweed seems to alter intestinal microflora preferentially, for instance, there was an increase in Lactobacillus and a decrease of Escherichia coli observed. These results suggest that Wakame seaweed can be used as supplement for pig feed to improve the gut health and immunity of pigs.

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“…The amount of additive seaweed in the diet was determined based on the data on the previous study (Suzuki et al . 2009).…”

Section: Methodsmentioning

confidence: 99%

“…The number of WBCs in the whole blood was measured with an autohemolytic counter (Celltac: Nihon Koden, Tokyo, Japan). The phagocyte activity was measured as described by Suzuki et al . (2009).…”

Section: Methodsmentioning

confidence: 99%

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Effect of dietary addition of seaweed and licorice on the immune performance of pigs

Katayama¹,

Fukuda²,

Okamura³

et al. 2010

Animal Science Journal

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In pig production, dietary additive antibiotics are usually used for growth stimulation and disease prevention, although there is public concern about the increased incidence of resistant antibiotics and food safety. It is possible that such antibiotics might be replaced by naturally derived products such as seaweed and licorice. In this study, we evaluated the effect of dietary addition of seaweed and licorice on enhancing the immune function in swine. The animals of each group (eight animals per group) were sensitized at day 42 and 49, and the immunoglobulin production and the expression of cytokines were detected by the ELISA and real-time PCR. As the results, saliva IgA production of the seaweed-treated group increased around five times compared to that of control (day 56). Delayed hypersensitivity reaction and IgG production of the seaweed-treated group increased around 1.8-2.0 times. In addition, enhanced saliva IgA production was detected at day 50 (around two times) and day 51 (around five times) by the licorice treatment, and lower expression level of tumor necrosis factor-α messenger RNA at day 51 (around 1/25) was observed in the licorice treatment. We conclude that the replacement of antibiotics by naturally derived dietary additives might be feasible for immune system enhancement.

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Effects of dietary seaweed, .BETA.-glucan and yeast on immunity and growth traits in growing pigs

Cited by 7 publications

References 11 publications

Correlated response of peripheral blood cytokines with selection for reduced mycoplasma pneumonia of swine lesions in Landrace pigs

Correlated response of peripheral blood cytokines with selection for reduced mycoplasma pneumonia of swine lesions in Landrace pigs

Addition of Wakame seaweed (Undaria pinnatifida) stalk to animal feed enhances immune response and improves intestinal microflora in pigs

Effect of dietary addition of seaweed and licorice on the immune performance of pigs

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