Effects of Dietary Copper Source and Level on Performance, Carcass Characteristics and Lipid Metabolism in Lambs

Abstract

An experiment was conducted to determine the effect of dietary copper (Cu) on performance, carcass characteristics and lipid metabolism in lambs. Fifty Dorper×Mongolia wether lambs (approximately 3 month of age; 23.8±0.6 kg of body weight) were housed in individual pens and were assigned randomly to one of five treatments. Treatments consisted of 1) control (no supplemental Cu), 2) 10 mg Cu/kg DM from Cu-lysine, 3) 20 mg Cu/kg DM from Cu-lysine, 4) 10 mg Cu/kg DM from tribasic copper chloride (Cu 2 (OH) 3 Cl; TBCC), 5) 20 mg Cu/kg DM from tribasic copper chloride. The Cu concentration was 6.74 mg/kg DM in the basal diet. Body weight was measured on two consecutive days at the start and the end of the 60-day experimental period. Blood samples were collected and then the lambs were slaughtered on d 60. Performance was not affected (p>0.05) by dietary Cu treatment. Cusupplemented and control lambs had similar hot carcass weight, dressing percentage and longissimus muscle area, but Cu supplementation, regardless of source and level, reduced (p<0.01) 12th rib backfat and kidney fat in lambs. Plasma tumor necrosis factor-alpha (TNF-α) and serum triglyceride concentrations were increased (p<0.05), total cholesterol concentrations were decreased (p<0.05) and nonesterified fatty acids (NEFA) concentrations tended to be increased (p<0.07) by Cu supplementation. However, Serum concentrations of HDL-cholesterol and LDL-cholesterol were not affected (p>0.05) by dietary treatment. Fatty acid profile of longissimus muscle was similar across treatments. These results indicate that Cu-lysine and TBCC are of similar availability in lambs. Cu supplementation given to Dorper×Mongolia wether lambs altered lipid metabolism. The reduction in backfat depth may be due to copper altering TNF-α metabolism in lambs. Supplementation of 10 or 20 mg Cu/kg DM showed similar effects on lipid metabolism in lambs.

Effects of various dietary levels of copper hydroxychloride on growth performance and tissue response in Pacific white shrimpLitopenaeus vannameifed practical diets

“…), lambs (Cheng et al . ), crucian carp Carassius auratus gibelio (Shao et al . ), blunt snout bream Megalobrama amblycephala (Shao et al .…”

“…Cu hydroxychloride possesses several valuable characteristics such as a lower solubility in water and very low chemical reactivity, thus making it an attractive Cu source in animal and aquatic feeds (Cromwell et al 1998). Several investigators have demonstrated Cu hydroxychloride as an effective copper source in pigs (Cromwell et al 1998), broilers (Luo et al 2005), lambs (Cheng et al 2008), crucian carp Carassius auratus gibelio (Shao et al 2010), blunt snout bream Megalobrama amblycephala (Shao et…”

Efeitos de fontes orgânicas de cobre e enxofre sobre os parâmetros bioquímicos no soro de ovinos

“…Em outro estudo com adição de 10 ou 20mg cobre/kg MS (cobre-lisina e cloreto do cobre tribásico) na alimentação de ovinos, Cheng et al (2008) observaram redução nos níveis de colesterol sanguíneo quando adicionado cobre, independente da fonte e aumento nas concentrações de triglicerídeos. Segundo Bakalli (1995) a síntese de colesterol pode ter relação com a suplementação de cobre, pois o aumento do cobre hepático pode diminuir a concentração de glutationa reduzida e consequentemente reduzir a enzima limitante na síntese e colesterol, denominada 3-hidroxi-3 metil glutaril coenzima A-redutase (HMG-CoA redutase).…”

Copper metabolism in goat-kid relationship at supplementation of inorganic and organic forms of copper

“…Views on the availability of Cu to the body when administered in various forms and concentrations are not identical (Spears, 1996;Cheng et al, 2008). In the study of Datta et al (2007) in kids fed inorganic (Cu sulfate) and organic (Cu proteinate) form of Cu it was observed that body weight increased linearly with increased dose of Cu.…”