Effects of dietary conjugated linoleic acid on the intestinal mucosal immunity of broiler chickens

Liu, Yong Xiang; Yang, Jian; Tang, G.; Jiang, D. F.

doi:10.1080/1828051x.2017.1305874

Cited by 4 publications

(2 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…CLA increased the SIgA mRNA and SIgA protein content in the jejunal mucosa. CLA treatment significantly increased PPAR γ expression in jejunum as well as lymphocyte proliferation, and the percent of T lymphocytes (CD8 + ) in Peyer's node of broilers ( 36 ).…”

Section: Discussionmentioning

confidence: 99%

Mechanism of Lysoforte in Improving Jejuna Morphology and Health in Broiler Chickens

Shi²,

Mesalam³

et al. 2022

Front. Vet. Sci.

View full text Add to dashboard Cite

Lysoforte (LFT) plays a vital role in maintaining broilers' health and intestinal morphology. However, the mechanism behind the effects of LFT improving intestinal morphology and health is still unclear. Therefore, this study was implemented to explore the central genes linked to the regulatory effect of LFT. Seventy-five newly hatched Cobb 500 male broilers were randomly divided into three groups: control, LFT500, and LFT1000 groups, with 25 chicks per group. The control chicks were provided with the basal diet, and the birds in LFT500 and LFT1000 groups were offered the same basal diet with 500 g/ton and 1,000 g/ton LFT, respectively. GSE94622 dataset consisted of the control and two LFT-treated groups (LFT500 and LFT1000). Jejuna samples were obtained from Gene Expression Omnibus (GEO). Totally 106–344 DEGs were obtained by comparing LFT500 and LFT1000 vs. control and LFT1000 vs. LFT500. Gene ontology (GO) enrichment suggested that the DEGs are mainly related to the phosphatidylethanolamine biosynthetic process and neuron projection extension. KEGG analysis suggested the DEGs were enriched in AGE-RAGE, fatty acid elongation, ECM-receptor interaction (ECMRI), glycerophospholipid metabolism, focal adhesion, unsaturated fatty acids biosynthesis, and ABC transporters. Moreover, 29 genes, such as REG4, GJB1, KAT2A, APOA5, SERPINE2, ELOVL1, ABCC2, ANKRD9, CYP4V2, and PISD, might be closely related to promoting jejuna morphology in broilers. Taken together, our observation enhances the understanding of LFT in maintaining intestinal architecture and the general health of broiler chickens.

show abstract

Section: Discussionmentioning

confidence: 99%

Mechanism of Lysoforte in Improving Jejuna Morphology and Health in Broiler Chickens

Shi²,

Mesalam³

et al. 2022

Front. Vet. Sci.

View full text Add to dashboard Cite

show abstract

“…An alternative explanation for the improved immune responses could be ingestion of immunomodulatory agents from the hedge itself; chickens are omnivorous and naturally explorative foragers (Brunberg et al, 2016), and it has been suggested that relatively modest changes in the nutrient composition of the diet can markedly affect the development of immune mechanisms (Williams et al, 2020). While detailing the exact composition of all the flora and fauna available in our hedge was beyond the scope of this study, some potential examples of immune-modulatory agents that may have contributed to this effect include willow leaf (Al-Fataftah and Abdelqader, 2013), phytochemicals, which are natural bioactive compounds that are derived from plants and incorporated into animal feed to enhance productivity (Lillehoj et al, 2018;Williams et al, 2020), polyunsaturated fatty-acids (Liu et al, 2017), and insects (Biasato et al, 2018;Benzertiha et al, 2020;Józefiak et al, 2020).…”

Section: Discussionmentioning

confidence: 99%

The Benefit of Hedgerow Access on the Health and Growth Rate of Pasture Raised Broiler Chickens

et al. 2021

View full text Add to dashboard Cite

Pasture rearing is an increasingly common option for small farms to produce humanely raised poultry products for an expanding market, however profit margins tend to be much lower for pastured poultry producers than for those that opt for conventional indoor rearing. Research into simple methods to optimize the growth and health of pasture-raised poultry can help small farmers maximize meat yields and decrease the morbidity and mortality of their flock, ultimately leading to higher profit margins and improved animal welfare. The objective of this study was to measure how the inclusion of mature, native foliage into pastures can impact the production performance and overall health status of two different popular breeds of commercial broiler chickens; fast-growing Cornish cross and slower growing Red rangers. During the finisher phase (30–78 days old), pastured chickens were separated by breed into either a treatment population with access to a mature bordering hedgerow, or a control population without access to a hedgerow. Weekly weight gain, daily feed intake and basic hematologic values were used to evaluate differences in the production performance and health status between each population. We found that hedge access led to a significant improvement in the rate of gain of the Cornish cross without an associated increase in feed intake, suggesting that the addition of hedges can increase meat yields in fast-growing broilers without increasing feed costs. Red rangers with hedge access demonstrated an improved ability to neutralize bacterial pathogens in whole blood and a lesser degree of hemodilution compared to control populations, suggesting improved immune function and a lower degree of heat stress in these populations. We conclude that the addition of natural environmental enrichment such as mature foliage to grass pastures can lead to improved production performance in fast-growing broilers and improvements in the health and immune function of slower growing broiler chickens.

show abstract

Conjugated linoleic acid (CLA) as a functional food: Is it beneficial or not?

Badawy

Liu

Guo

et al. 2023

Food Research International

View full text Add to dashboard Cite

Effects of dietary conjugated linoleic acid on the intestinal mucosal immunity of broiler chickens

Cited by 4 publications

References 33 publications

Mechanism of Lysoforte in Improving Jejuna Morphology and Health in Broiler Chickens

Mechanism of Lysoforte in Improving Jejuna Morphology and Health in Broiler Chickens

The Benefit of Hedgerow Access on the Health and Growth Rate of Pasture Raised Broiler Chickens

Conjugated linoleic acid (CLA) as a functional food: Is it beneficial or not?

Contact Info

Product

Resources

About