Effects of Depression and Anxiety on Microvascular Decompression Outcome for Trigeminal Neuralgia Patients

Chang, Bowen; Zhu, Wanchun; Li, Shiting

doi:10.1016/j.wneu.2019.04.194

Cited by 21 publications

(20 citation statements)

References 30 publications

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“…The Hamilton Depression Rating Scale (HDRS) and the Hamilton Anxiety Rating Scale (HARS) are the most widely used measures of patient depression and anxiety, respectively. 21,22 A score of 0 to 7 was considered normal, a score of >7 was considered to indicate depression or anxiety, and higher scores indicated greater severity of depression or anxiety.…”

Section: Survey Instrumentsmentioning

confidence: 99%

Predictors of caregiver burden in patients with neurologic Wilson disease

Zheng

Fan

et al. 2020

J Int Med Res

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Objectives Caregiver burden in neurologic Wilson disease (NWD) has received little attention. We investigated predictors of caregiver burden in Chinese NWD patients. Methods Participants in this retrospective study were NWD patients admitted to The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine from 1 August to 31 December 2019. Sociodemographic information was recorded for caregivers and NWD patients. Caregiver burden was evaluated using the Caregiver Burden Inventory (CBI). Cognitive impairment, functional problems, depression and anxiety were evaluated by professional interviewers. Path analysis was used to evaluate predictors of CBI scores. Results Sixty NWD patients were enrolled (mean age: 21.35 ± 4.89 years; mean NWD duration: 7.85 ± 3.11 years). The mean CBI score was 52.00 ± 17.16. Care duration had a significant direct effect on CBI score after controlling for confounders (r = 0.493). Cognitive impairment (r = −0.426), functional problems (r = 0.581), depression (r = 0.349) and anxiety (r = 0.317) had significant indirect effects on CBI score. Conclusion Caregivers of NWD patients may experience a medium level of caregiver burden. NWD duration, cognitive impairment, functional problems, depression and anxiety in NWD patients may be useful predictors of caregiver burden.

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Section: Survey Instrumentsmentioning

confidence: 99%

Predictors of caregiver burden in patients with neurologic Wilson disease

Zheng

Fan

et al. 2020

J Int Med Res

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“…According to our findings, anxiety and depression could potentially serve as risk factors indicating dismal MVD outcomes for adolescent HFS cases, and such result was consistent with those in other studies on cranial nerve disease. [ 13 , 18 ] Anxiety and depression have negative effect on relevant physiopathological mechanism that affects the treatment course for disease, and this will then affect patient medical conditions, which was related to hypertarachia of certain biological pathways as well as depression of central nervous system (CNS). [ 5 , 19 ] In our study, anxiety and depression showed close correlation with HFS severity; therefore, it was recommended that the collaboration between the neurosurgery departments and psychiatric teams should be increased to assess HDRS and HARS among HFS cases.…”

Section: Discussionmentioning

confidence: 99%

Roles of preoperative anxiety and depression in the outcomes of microvascular decompression in hemifacial spasm for adolescent patients

Wei

Wang

et al. 2021

Medicine

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Hemifacial spasm (HFS) has been recognized as the frequently occurring disease of cranial nerve. At the same time, several articles indicate that, dystonia results in certain psychological disorders. Consequently, this study aimed to examine the association of preoperative depression and anxiety with HFS severity; meanwhile, the role in microvascular decompression (MVD) outcomes after surgery among adolescent patients was also examined. All cases had been classified as two groups based on MVD outcomes among HFS cases; in addition, the preoperative Hamilton anxiety rating scale (HARS) and the Hamilton depression rating scale (HDRS) scores were compared between patients not and still suffering from spasm. Moreover, the multiple logistic regression model was employed in assessing the relationship between preoperative HARS as well as HDRS scores and outcomes of adolescent cases undergoing MVD. The preoperative HARS and HDRS scores showed positive correlation with Cohen spasm grades in HFS patients. Meanwhile, compared with spasm-free group, patients of persistent spams group had apparently higher preoperative HARS and HDRS scores. Our results suggest that, preoperative anxiety and depression status show close association with HFS severity, and they could also impact the MVD outcomes for adolescent cases.

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“…Anxiety and depression are associated with more failures after MVD surgery [19]. In the first case, the patient had panic attacks, possibly increasing her anxiety and sensitizing the patient to perceive more pain.…”

Section: Discussionmentioning

confidence: 99%

Trigeminal neuralgia management after microvascular decompression surgery: two case reports

Hwang

Gomez-Marroquin

Enciso

et al. 2020

J Dent Anesth Pain Med

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Trigeminal neuralgia (TN) involves chronic neuropathic pain, characterized by attacks of repeating short episodes of unilateral shock-like pain, which are abrupt in onset and termination. Anticonvulsants, such as carbamazepine, are the gold standard first-line drugs for pharmacological treatment. Microvascular decompression (MVD) surgery is often the course of action if pharmacological management with anticonvulsants is unsuccessful. MVD surgery is an effective therapy in approximately 83% of cases. However, persistent neuropathic pain after MVD surgery may require reintroduction of pharmacotherapy. This case report presents two patients with persistent pain after MVD requiring reintroduction of pharmacological therapy. Although MVD is successful for patients with failed pharmacological management, it is an invasive procedure and requires hospitalization of the patient. About one-third of patients suffer from recurrent TN after MVD. Often, alternative treatment protocols, including the reintroduction of medications, may be necessary to achieve improvement. This case report presents two cases of post-MVD recurrent pain. Further research is lacking on the success rates of subsequent medication therapy after MVD has proven less effective in managing TN.

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Effects of Depression and Anxiety on Microvascular Decompression Outcome for Trigeminal Neuralgia Patients

Cited by 21 publications

References 30 publications

Predictors of caregiver burden in patients with neurologic Wilson disease

Predictors of caregiver burden in patients with neurologic Wilson disease

Roles of preoperative anxiety and depression in the outcomes of microvascular decompression in hemifacial spasm for adolescent patients

Trigeminal neuralgia management after microvascular decompression surgery: two case reports

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