Effects of depression and anxiety on quality of life of patients with rheumatoid arthritis, knee osteoarthritis and fibromyalgia syndrome

Psychological Factors Associated with Response to Treatment in Rheumatoid Arthritis

“…Studies have shown that quality of life is significantly lower in patients with RA than in patients with other inflammatory conditions, because their depression or anxiety scores are higher [93,94]. Kojima et al (2009) suggested that disease activity evaluated by routine objective clinical examinations does not mirror the physical and mental quality of life of RA patients [81].…”

Are Psychological Factors Associated with Pain Worsening in Individuals with Knee Osteoarthritis? A Systematic Review

“…RoBANS contains six domains: the selection of participants, confounding variables, the measurement of exposure, the blinding corresponded to evidence level II. Anxiety was investigated by five studies [14,18,19,28,31], one of these studies was of a prospective cohort design and showed no causal relationship with pain worsening. Three studies [19,26,28] examined the relationship with fear and pain worsening, but statistical significance was not confirmed.…”

Disabling Osteoarthritis and Symptomatic Anxiety: Impact and Implications

“…Not unexpectedly, a related prospective study by Dieppe et al (2000) found adults with osteoarthritis examined over an eight year period generally had a poor outcome with high levels of physical disability, as well as anxiety, and a high level of healthcare resource utilization, especially if they had knee osteoarthritis. The high rate of anxiety symptoms in people with osteoarthritis, and its strong negative correlation with their functional scores (Ozcetin et al, 2007) is not unexpected given its association with both pain and with obesity (Witlink et al, 2010), and avoidance behaviors (Scopaz et al, 2009). Indeed allied research shows obesity, a highly prevalent condition observed among adults with osteoarthritis can significantly increase the risk for mental illness, and the finding that the cohort studied by Marks (2007) tended to show higher body mass indices in those with anxiety histories supports this relationship.…”