Effects of Deepwater Horizon crude oil on ocular development in two estuarine fish species, red drum (Sciaenops ocellatus) and sheepshead minnow (Cyprinodon variegatus)

Magnuson, Jason T.; Khursigara, Alexis J.; Allmon, Elizabeth; Esbaugh, Andrew J.; Roberts, Aaron P.

doi:10.1016/j.ecoenv.2018.09.087

Cited by 67 publications

(42 citation statements)

References 30 publications

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“…Crude oil-induced eye developmental defects are well documented. Both reduced eye size (anapthalmia) and reduced size with abnormalities (microphtalmia) are observed Lie et al, 2019;Magnuson et al, 2018). In the present study, eye size was mainly affected in the early exposure, where we find the most severe developmental and functional abnormalities.…”

Section: Morphological Abnormalitiessupporting

confidence: 54%

Untangling mechanisms of crude oil toxicity: linking gene expression, morphology and PAHs at two developmental stages in a cold-water fish

Sørhus¹,

Donald²,

Dasilva

et al. 2020

Preprint

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Early life stages of fish are highly sensitive to crude oil exposure and thus, short term exposures during critical developmental periods could have detrimental consequences for juvenile survival. To obtain a broader understanding of the mechanisms behind crude oil toxicity, we administered crude oil to Atlantic haddock (Melanogrammus aeglefinus) in short term (3-day) exposures at two developmental time-points, before and after onset of heartbeat. A frequent sampling regime enabled us to determine and link immediate PAH uptake, metabolite formation and gene expression changes (cyp1a,b,c,d, bmp10, abcb1 and rhag). In general, the embryotoxic consequences were more severe in the earliest exposure, and oil droplet fouling enhanced the toxicity. This study detected circulation-independent, oil-induced gene expression changes and separated phenotypes linked to proliferation, growth and disruption of formation events at early and late developmental stages. A greater understanding of crude oil toxicity is essential for predicting the consequences of oil spills.Graphic abstractHighlightsOil droplet fouling occurred in the whole water column and increased the oil toxicity.Early exposure resulted in higher PAH uptake due to lower metabolism resulting in more severe abnormalities.A rapid and circulation-indepenent regulation of bmp10 suggested a direct oil-induced effect on calcium homeostasis.Expression of rhag indicated a direct oil-induced effect on osmoregulatory cells and osmoregulation.Severe eye abnormalities especially in the late exposure was linked to inappropriate overexpression of cyp1b in the eyes.

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Section: Morphological Abnormalitiessupporting

confidence: 54%

Untangling mechanisms of crude oil toxicity: linking gene expression, morphology and PAHs at two developmental stages in a cold-water fish

Sørhus¹,

Donald²,

Dasilva

et al. 2020

Preprint

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“…These results indicate that an abnormal development of the heart in the 3-OHBcP-exposed medaka embryo had occurred. Also, the expression of genes related to eye development (lens, beaded filament, and crystalline) increased due to 3-OHBcP exposure, as shown above [60]. Furthermore, the expression of genes related to muscle development, energy supply, and stress-response proteins significantly changed during early development in medaka.…”

Section: Toxicity Of Pahs On the Early Development Of Fishmentioning

confidence: 63%

“…In crude oil from the Deepwater Horizon oil spill, which included three-ring PAH congeners (i.e., phenanthrenes), the mechanism of embryonic heart failure was demonstrated through two pathways: (1) the inhibition of the inwardly rectifying potassium channel, which drives the repolarization of cardiac action potentials; and (2) a disruption of intracellular calcium cycling in cardiomyocytes, either by blocking the ryanodine receptor or the sarcoplasmic reticulum calcium pump [59]. In addition to impacting cardiac function, PAHs contained in crude oil have been shown to cause the dysregulation of genes important in eye development and function, as well as morphological abnormalities of the eye [60]. The mean diameters of retinal layers and optomotor response were significantly reduced in oil-exposed larvae [60].…”

Section: Toxicity Of Pahs On the Early Development Of Fishmentioning

confidence: 99%

“…In addition to impacting cardiac function, PAHs contained in crude oil have been shown to cause the dysregulation of genes important in eye development and function, as well as morphological abnormalities of the eye [60]. The mean diameters of retinal layers and optomotor response were significantly reduced in oil-exposed larvae [60]. Embryos particularly sensitive to dispersed crude oil have been reported [61].…”

Section: Toxicity Of Pahs On the Early Development Of Fishmentioning

confidence: 99%

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Toxicities of Polycyclic Aromatic Hydrocarbons for Aquatic Animals

Honda

Suzuki

2020

IJERPH

385

126

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Polycyclic aromatic hydrocarbons (PAHs) are organic compounds that are widely distributed in the air, water, and soil. Recently, the amount of PAHs derived from fuels and from incomplete combustion processes is increasing. In the aquatic environment, oil spills directly cause PAH pollution and affect marine organisms. Oil spills correlate very well with the major shipping routes. Furthermore, accidental oil spills can seriously impact the marine environment toxicologically. Here, we describe PAH toxicities and related bioaccumulation properties in aquatic animals, including invertebrates. Recent studies have revealed the toxicity of PAHs, including endocrine disruption and tissue-specific toxicity, although researchers have mainly focused on the carcinogenic toxicity of PAHs. We summarize the toxicity of PAHs regarding these aspects. Additionally, the bioaccumulation properties of PAHs for organisms, including invertebrates, are important factors when considering PAH toxicity. In this review, we describe the bioaccumulation properties of PAHs in aquatic animals. Recently, microplastics have been the most concerning environmental problem in the aquatic ecosystem, and the vector effect of microplastics for lipophilic compounds is an emerging environmental issue. Here, we describe the correlation between PAHs and microplastics. Thus, we concluded that PAHs have a toxicity for aquatic animals, indicating that we should emphasize the prevention of aquatic PAH pollution.

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“…The Deepwater Horizon (DWH) oil spill was the most emblematic and largest marine incident in history. It occurred from April 20 to July 14 in 2010, releasing around 5 million barrels of oil and gas into the Gulf of Mexico (Magnuson et al, 2018). Along with DWH, the 1989 Exxon Valdez oil outpour in Alaska spilled 10.8 million US gallons (37,000 metric tons) of crude oil, and it is considered to be one of the worst human-caused environmental disasters and the most massive oil spill in U.S. waters (US National Academy of Science, 2004).…”

mentioning

confidence: 99%

The environmental impacts of 2019 oil spill on the Brazilian coast: Overview

Disner¹,

Torres²

2020

Rev. Bras. Gest. Amb. Sustent.

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The oil spill off the Brazilian coast, which reached especially the Northeast in 2019, is known as the biggest disaster of its kind in the country's history. Accidents of this type are not new; however, this episode had enormous proportions with 11 states, 130 municipalities, and more than 1,000 locations affected by oil stains or residues. Considering the extent of this environmental tragedy associated with the Brazilian biodiversity peculiarities is immeasurable the damages to fauna and protected areas, especially those that are more sensitive, such as mangroves and coral reefs. It is known that the oil source is Venezuela, but those responsible for the disaster are not known yet. The neglect in investigating events and decision making to deal with the incident aggravated the effects on habitats and local communities. The first occurrence on the coast happened on August 30, 2019, and the most significant number of affected locations was recorded during November. However, even without a complete solution of the case, in January 2020, the monitoring and evaluation group responsible for monitoring, remediation, and protection actions, officially announce the beginning of the demobilization protocol, establishing the termination points, which represent the end of monitoring in most of the areas. Contradictorily, in some locations considered sensitive, the end of the work will be carried out “even with the significant presence of oil in the area”. Studies in the literature indicate that highly weathered oil, which has a high molecular weight and low solubility PAHs, can have toxic effects as representative or higher than its non-weathered counterpart. These findings contradict a classic paradigm that crude oil with low molecular weight and more volatile PAHs are primarily responsible for toxicity. Regardless of the damages caused by the activities of total oil removal compared to natural degradation, there is a disregard for this issue, a deficit of environmental agencies employees and investments in this sector. Given the initiative to demobilize activities related to this serious accident, this review seeks to contextualize similar accidents, synthesize the events, dimensions, and environmental consequences related to the most significant ecological disaster on the Brazilian coast and discuss its likely environmental impacts considering the physical-chemical characteristics of the pollutant. In recent years, Brazil has been the scene of unprecedented disasters. The oil in the Northeast, along with the Mariana and Brumadinho dam rupture and the fires in the Amazon shows the lack of critical assessment of the environmental issue in Brazil, and what appears to be a society plan that, through structural measures, allows cases of environmental degradation to happen with impunity and the conservation of natural resources is genuinely not a priority of government actions.

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Effects of Deepwater Horizon crude oil on ocular development in two estuarine fish species, red drum (Sciaenops ocellatus) and sheepshead minnow (Cyprinodon variegatus)

Cited by 67 publications

References 30 publications

Untangling mechanisms of crude oil toxicity: linking gene expression, morphology and PAHs at two developmental stages in a cold-water fish

Untangling mechanisms of crude oil toxicity: linking gene expression, morphology and PAHs at two developmental stages in a cold-water fish

Toxicities of Polycyclic Aromatic Hydrocarbons for Aquatic Animals

The environmental impacts of 2019 oil spill on the Brazilian coast: Overview

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