Effects of day-time feeding on murine skeletal muscle growth and synthesis

Aoyama, Shogo; Kojima, Shuichi; Sasaki, Keisuke; Shimoda, Takeru; Takahashi, Kengo; Hirooka, Rina; Tahara, Yu; Shibata, Shigenobu

doi:10.1016/j.jnim.2019.100099

Cited by 4 publications

(3 citation statements)

References 27 publications

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Section: Therapeutic Potential Of Chrono-nutrition Against Are-related Muscle Dysfunctionsmentioning

confidence: 99%

“…conducted during the rest phase (day time) (Abe et al, 2019;Aoyama et al, 2019). The TRF conducted during the active phase has beneficial effects on muscle growth and muscular protein synthesis compared with that conducted during the rest phase (Abe et al, 2019;Aoyama et al, 2019). Taken together, considering that muscle loss is particularly observed in glycolytic muscle fibers of patients with sarcopenia, ITAD feeding during the active phase may be an effective nutritional intervention for the prevention of sarcopenia.…”

Section: Therapeutic Potential Of Chrono-nutrition Against Are-related Muscle Dysfunctionsmentioning

confidence: 99%

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Chrono-Nutrition Has Potential in Preventing Age-Related Muscle Loss and Dysfunction

2021

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The mammalian circadian clock systems regulate the day–night variation of several physiological functions such as the sleep/wake cycle and core body temperature. Disturbance in the circadian clock due to shiftwork and chronic jetlag is related to the risk of several disorders such as metabolic syndrome and cancer. Recently, it has been thought that shiftwork increases the risk of sarcopenia which is characterized by age-related decline of muscle mass and its dysfunctions including muscle strength and/or physical performance. First, we summarize the association between circadian rhythm and the occurrence of sarcopenia and discuss its mechanistic insight by focusing on the muscle function and molecular clock gene in knockout or mutant mice. The clock gene knockout or mutant mice showed early aging phenotypes, including low survival rate and muscle loss. It suggests that improvement in the disturbance of the circadian clock plays an important role in the aging process of healthy muscles. Nutritional intake has the potential to augment muscle growth and entrain the peripheral clock. Second, we discuss the potential of chrono-nutrition in preventing aging-related muscle loss and dysfunction. We also focus on the effects of time-restricted feeding (TRF) and the distribution of protein intake across three meals.

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Section: Therapeutic Potential Of Chrono-nutrition Against Are-related Muscle Dysfunctionsmentioning

confidence: 99%

Section: Therapeutic Potential Of Chrono-nutrition Against Are-related Muscle Dysfunctionsmentioning

confidence: 99%

Chrono-Nutrition Has Potential in Preventing Age-Related Muscle Loss and Dysfunction

2021

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“…Muscle mass is controlled by the balance between muscle synthesis and degradation, which plays an important role in energy metabolism and exercise (Aoyama et al., 2019). The quality of muscle is primarily influenced by nutritional status and physical activity (Cohen, Nathan, & Goldberg, 2015).…”

Section: Introductionmentioning

confidence: 99%

Hydrolyzed peptides from purple perilla ( Perilla frutescens L. Britt.) seeds improve muscle synthesis and exercise performance in mice

Liu

Wei

et al. 2020

J. Food Biochem.

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The purple perilla (Perilla frutescens L. Britt.) seed peptides (PPSP) were obtained and their improvement of muscle synthesis and exercise performance was investigated in this work. Results showed that the weight-average molecular weight of the PPSP was 869 Dalton. The PPSP were rich in branched-chain amino acids (18.82 g/100 g) and anti-fatigue amino acids, including glutamate (Glu), aspartic acid (Asp), and arginine (Arg). After the administration of PPSP at 1.2 g kg-1 day-1 for 4 weeks, the muscle coefficient and muscle fiber thickness in mice displayed a distinct (p < .05) increase via the upregulation of myogenic differentiation (MyoD) and myogenin (MyoG). The improved muscle strength and exercise tolerance were also observed. Simultaneously, the levels of the biochemical blood markers associated with fatigue and the glycogen degradation in liver and muscle were significantly (p < .05) suppressed. These results suggested that PPSP could effectively promote muscle synthesis and ameliorate exercise fatigue. Practical applications Purple perilla is an annual herbal plant and widely grown in Asian countries as an important crop and food. It is believed that the protein content of purple perilla seeds can reach 23.7%, and the protein is rich in essential amino acids. However, the information about the beneficial effects of their proteins or peptides on muscle synthesis and anti-exercise fatigue were still limited. The present results discovered that the PPSP can effectively promote the growth of muscle tissue and improve exercise tolerance. It is indicated that PPSP may have a potential application value in partly or completely replacing animal proteins such as whey protein.

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Time-of-Day-Dependent Physiological Responses to Meal and Exercise

Aoyama

Shibata

2020

Front. Nutr.

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The mammalian circadian clock drives the temporal coordination in cellular homeostasis and it leads the day-night fluctuation of physiological functions, such as sleep/wake cycle, hormonal secretion, and body temperature. The mammalian circadian clock system in the body is classified hierarchically into two classes, the central clock in the suprachiasmatic nucleus (SCN) of the hypothalamus and the peripheral clocks in peripheral tissues such as the intestine and liver, as well as other brain areas outside the SCN. The circadian rhythm of various tissue-specific functions is mainly controlled by each peripheral clock and partially by the central clock as well. The digestive, absorptive, and metabolic capacities of nutrients also show the day-night variations in several peripheral tissues such as small intestine and liver. It is therefore indicated that the bioavailability or metabolic capacity of nutrients depends on the time of day. In fact, the postprandial response of blood triacylglycerol to a specific diet and glucose tolerance exhibit clear time-of-day effects. Meal frequency and distribution within a day are highly related to metabolic functions, and optimal time-restricted feeding has the potential to prevent several metabolic dysfunctions. In this review, we summarize the time-of-day-dependent postprandial response of macronutrients to each meal and the involvement of circadian clock system in the time-of-day effect. Furthermore, the chronic beneficial and adverse effects of meal time and eating pattern on metabolism and its related diseases are discussed. Finally, we discuss the timing-dependent effects of exercise on the day-night variation of exercise performance and therapeutic potential of time-controlled-exercise for promoting general health.

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Effects of day-time feeding on murine skeletal muscle growth and synthesis

Cited by 4 publications

References 27 publications

Chrono-Nutrition Has Potential in Preventing Age-Related Muscle Loss and Dysfunction

Chrono-Nutrition Has Potential in Preventing Age-Related Muscle Loss and Dysfunction

Hydrolyzed peptides from purple perilla ( Perilla frutescens L. Britt.) seeds improve muscle synthesis and exercise performance in mice

Time-of-Day-Dependent Physiological Responses to Meal and Exercise

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