Effects of DASH diet on lipid profiles and biomarkers of oxidative stress in overweight and obese women with polycystic ovary syndrome: A randomized clinical trial

Asemi, Zatollah; Samimi, Mansooreh; Tabassi, Zohreh; Shakeri, Hossein; Sabihi, Sima-Sadat; Esmaillzadeh, Ahmad

doi:10.1016/j.nut.2014.03.008

Cited by 97 publications

(97 citation statements)

References 51 publications

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“…Although the prospective associations of DASH score with long‐term outcomes were independent of baseline blood pressure, we do not know if subjects with higher DASH scores continued to have better‐controlled blood pressure over time, which leaves the possibility that the beneficial effects of the DASH diet are mediated by blood pressure. Previous studies showed that the DASH diet improves the lipid profile by lowering triglyceride levels, total cholesterol, and LDL‐cholesterol concentration 44, 45, 46. In the baseline characteristics of this study, we observe lower triglyceride levels and higher HDL concentrations in the highest tertile of the DASH score compared to the lowest tertile.…”

Section: Discussionsupporting

confidence: 56%

Dietary Approach to Stop Hypertension (DASH) diet and risk of renal function decline and all-cause mortality in renal transplant recipients

Osté

Gomes-Neto

Corpeleijn

et al. 2018

American Journal of Transplantation

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Renal transplant recipients (RTR) are at risk of decline of graft function and premature mortality, with high blood pressure as an important risk factor for both. To study the association of the Dietary Approach to Stop Hypertension (DASH) diet with these adverse events, we conducted a prospective cohort study of adult RTR. Dietary data were collected using a validated 177‐item food frequency questionnaire and an overall DASH‐score was obtained. We included 632 stable RTR (mean ± standard deviation age 53.0 ± 12.7 years, 57% men). Mean DASH score was 23.8 ± 4.7. During median follow‐up of 5.3 (interquartile range, 4.1‐6.0) years, 119 (18.8%) RTR had renal function decline, defined as a combined endpoint of doubling of serum creatinine and death‐censored graft failure, and 128 (20.3%) died. In Cox‐regression analyses, RTR in the highest tertile of the DASH score had lower risk of both renal function decline (hazard ratio [HR] = 0.57; 95% confidence interval [CI], 0.33‐0.96, P = .03) and all‐cause mortality (HR = 0.52; 95%CI, 0.32‐0.83, P = .006) compared to the lowest tertile, independent of potential confounders. Adherence to a DASH‐style diet is associated with lower risk of both renal function decline and all‐cause mortality. These results suggest that a healthful diet might benefit long‐term outcome in RTR.

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Section: Discussionsupporting

confidence: 56%

Dietary Approach to Stop Hypertension (DASH) diet and risk of renal function decline and all-cause mortality in renal transplant recipients

Osté

Gomes-Neto

Corpeleijn

et al. 2018

American Journal of Transplantation

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“…An 8-wk RCT in 48 women with polycystic ovary syndrome in Iran showed that adherence to the DASH diet than to a control diet resulted in a significant decrease in serum triglycerides and VLDLs (31). An RCT in 144 overweight or obese, unmedicated, hypertensive adults showed that the DASH diet with aerobic exercise and caloric restriction compared with the DASH diet alone and with usual diet controls was associated with significant decreases in 1 Geometric means and 95% CIs were calculated with the use of multiple linear regression models.…”

Section: Discussionmentioning

confidence: 99%

Dietary patterns and cardiometabolic and endocrine plasma biomarkers in US women

AlEssa

Malik

Yuan

et al. 2017

The American Journal of Clinical Nutrition

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Background: Healthful dietary patterns have been associated with lower risks of type 2 diabetes and coronary artery disease, but their relations with intermediate markers of cardiometabolic and endocrine health are less established. Objective: We evaluated the Dietary Approaches to Stop Hypertension (DASH), the alternate Mediterranean diet (aMED), and the Alternate Healthy Eating Index (aHEI) diet-quality scores with cardiometabolic and endocrine plasma biomarkers in US women. Design: The trial was a cross-sectional analysis of 775 healthy women in the Women's Lifestyle Validation Study that was conducted within the NHS (Nurses' Health Study) and NHS II longitudinal cohorts. Multiple linear regression models adjusted for potential confounders were used to estimate associations between quartiles of dietary pattern-adherence scores that were derived from a food-frequency questionnaire and plasma biomarker concentrations that were collected simultaneously. Results: In multivariable models in which highest and lowest quartiles of dietary pattern scores were compared, 1) DASH was significantly associated with higher concentrations of high-density lipoprotein (9%) and sex-hormone binding globulin (SHBG) (21%), and lower concentrations of leptin (28%), triglycerides (19%), and C-peptide (4%) (all P-trend # 0.04); 2) the aMED was associated with 19% higher SHBG and 16% lower triglycerides (P-trend = 0.02 and 0.003, respectively); and 3) the aHEI was associated with significantly higher concentrations of insulin (16%) and SHBG (19%) and lower concentrations of leptin (18%) (all P-trend # 0.02). Further adjustment for body mass index (BMI) attenuated these associations but remained significant for 1) DASH with leptin and triglycerides and 2) the aMED with triglycerides (all P-trend # 0.03). Conclusions: Adherence to healthful dietary patterns is associated with favorable concentrations of many cardiometabolic and endocrine biomarkers. These relations are mediated in part by BMI. Am J Clin Nutr 2017;105:432-41.

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“…76,78,[90][91][92]105,106,152 Moderately low-carbohydrate, high-fat diets have been shown to decrease fasting insulin and AUC for insulin and to increase insulin sensitivity in three trials in women with PCOS. [90][91][92] In one trial, a high-fat, moderately low-carbohydrate eucaloric diet resulted in greater reductions in body fat, intra-abdominal adipose tissue, subcutaneous abdominal adipose tissue and intermuscular adipose tissue compared to a control diet.…”

Section: Dietary Fat and Pcosmentioning

confidence: 99%

“…99,107 Asemi and Esmaillzadeh 78 demonstrated that adherence to DASH eating pattern, compared to a control diet based on Iranian traditional foods, resulted in greater reductions in body weight, BMI, WC, hip circumference (HC), serum insulin levels, IR, hsCRP and TG compared to the control diet in women with PCOS. 106 Similarly, another trial showed that adherence to the DASH diet for 12 weeks had beneficial effects on weight loss, serum AMH, markers of insulin metabolism, SHBG, FAI, plasma nitric oxide and malondialdehyde levels among women with PCOS.…”

mentioning

confidence: 98%

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Nutritional support and dietary interventions for women with polycystic ovary syndrome

Papavasiliou¹,

Papakonstantinou²

2017

NDS

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Polycystic ovary syndrome (PCOS) is a common endocrine disorder in reproductiveaged women, which leads to reproductive, metabolic and hormonal abnormalities. Hyperinsulinemia, insulin resistance, androgen excess, ovulatory dysfunction, polycystic ovaries, gonadotropin abnormalities, obesity, adipose tissue dysfunction, difficulty to conceive and high-risk pregnancy are the most common PCOS-associated complications. The aim of this review was to describe and evaluate the effects of dietary interventions on PCOS-associated outcomes and to provide some evidence-based dietary advice for use in clinical practice. There is no optimal diet or macronutrient composition for PCOS. However, lifestyle modification, including a small-to-moderate weight loss of 5-10% (combined diet with regular physical activity) with any dietary pattern of choice, depending on the individuals' preferences, culture, habits and metabolic needs (ie, Mediterranean diet, Dietary Approaches to Stop Hypertension [DASH] diet or moderately low-carbohydrate diets [30-45% of energy]), as well as alternative dietary interventions, including small, frequent meal (five to six meals daily) consumption at regular times, with the majority of carbohydrates consumed at lunch time or equally distributed throughout the day, seems to offer the evidence-based first-line strategy for the management of PCOS symptoms and insulin resistance. No conclusions can be drawn at this time for high protein diets, polyunsaturated fatty acids or micronutrient supplementation.

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Effects of DASH diet on lipid profiles and biomarkers of oxidative stress in overweight and obese women with polycystic ovary syndrome: A randomized clinical trial

Cited by 97 publications

References 51 publications

Dietary Approach to Stop Hypertension (DASH) diet and risk of renal function decline and all-cause mortality in renal transplant recipients

Dietary Approach to Stop Hypertension (DASH) diet and risk of renal function decline and all-cause mortality in renal transplant recipients

Dietary patterns and cardiometabolic and endocrine plasma biomarkers in US women

Nutritional support and dietary interventions for women with polycystic ovary syndrome

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