Effects of Cyproterone-Containing Oral Contraceptive on Hormonal Levels in Polycystic Ovarian Disease

Calaf-Alsina, Joaquim; Rodrı́guez-Espinosa, José; Cabero-Roura, A; Lenti-Paoli, O; Mora-Brugués, Josefina; Esteban-Altirriba, J.

doi:10.1097/00006254-198710000-00015

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Variations In Oral Contraceptive Preparation Therapy1

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1988

1989

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“…Other investigators have successfully used an other antiandrogen, cyproterone acetate, as the pro gestational agent in an OCP for the treatment of hirsutism. 63 The cyclic administration of estrogens with regular monthly progestin withdrawals, as in menopausal hormone replacement, is moderately ef fective in the treatment of hirsutism. 64 Estrogen alone, however, produces significantly less inhibi tion of circulating levels of gonadotropins than do estrogen/progestin combinations 6 and may increase adrenal androgen secretions.…”

Section: Variations In Oral Contraceptive Preparation Therapymentioning

confidence: 99%