Effects of curcumin and its adjuvant on TPC1 thyroid cell line

Esposito, Teresa; Lucariello, Angela; Hay, Eleonora; Contieri, Marcella; Tammaro, Pasquale; Varriale, Bruno; Guerra, Germano; Luca, Antonio De; Perna, Angelica

doi:10.1016/j.cbi.2019.03.031

Cited by 32 publications

(13 citation statements)

References 38 publications

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“…Curcumin has been widely used for centuries for the treatment of several diseases, its usage dating back more than 2500 years in Asia, especially in traditional Indian medicine (Ayurveda) [33]. It has been utilized for various health problems, including several skin diseases, wounds, sinusitis, eye infection, rheumatism, dyspepsia, stress and depression Helicobacter pylori infection, peptic ulcer and irritable bowel syndrome, and placental diseases [34][35][36][37][38][39][40][41]. Interestingly, the first scientific study on the therapeutic properties of curcumin was published in 1937 [42].…”

Section: Phytochemicals As Anti-cancer Molecules: the Example Of Curcmentioning

confidence: 99%

Curcumin as an Anticancer Agent in Malignant Mesothelioma: A Review

Baldi

Luca

Maiorano

et al. 2020

IJMS

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Malignant mesothelioma is an infrequent tumor that initiates from the mesothelial cells lining of body cavities. The great majority of mesotheliomas originate in the pleural cavity, while the remaining cases initiate in the peritoneal cavity, in the pericardial cavity or on the tunica vaginalis. Usually, mesotheliomas grow in a diffuse pattern and tend to enclose and compress the organs in the various body cavities. Mesothelioma incidence is increasing worldwide and still today, the prognosis is very poor, with a reported median survival of approximately one year from presentation. Thus, the development of alternative and more effective therapies is currently an urgent requirement. The aim of this review article was to describe recent findings about the anti-cancer activity of curcumin and some of its derivatives on mesotheliomas. The potential clinical implications of these findings are discussed.

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Section: Phytochemicals As Anti-cancer Molecules: the Example Of Curcmentioning

confidence: 99%

Curcumin as an Anticancer Agent in Malignant Mesothelioma: A Review

Baldi

Luca

Maiorano

et al. 2020

IJMS

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“…Recently, vitamin E has been found in combination with curcumine and piperine to exert inhibitory effect on cell proliferation through influencing cell cycle regulators such as β-catenin, cyclin D1 and p53 in human thyroid papillary carcinoma cells; however, further studies are necessary to candidate vitamin D as alternative cancer therapy [91].…”

Section: Vitamin Ementioning

confidence: 99%

Nutraceuticals in Thyroidology: A Review of in Vitro, and in Vivo Animal Studies

et al. 2020

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Nutraceuticals are defined as a food, or parts of a food, that provide medical or health benefits, including the prevention of different pathological conditions, and thyroid diseases, or the treatment of them. Nutraceuticals have a place in complementary medicines, being positioned in an area among food, food supplements, and pharmaceuticals. The market of certain nutraceuticals such as thyroid supplements has been growing in the last years. In addition, iodine is a fundamental micronutrient for thyroid function, but also other dietary components can have a key role in clinical thyroidology. Here, we have summarized the in vitro, and in vivo animal studies present in literature, focusing on the commonest nutraceuticals generally encountered in the clinical practice (such as carnitine, flavonoids, melatonin, omega-3, resveratrol, selenium, vitamins, zinc, and inositol), highlighting conflicting results. These experimental studies are expected to improve clinicians’ knowledge about the main supplements being used, in order to clarify the potential risks or side effects and support patients in their use.

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“…WNT signaling is widely known to modulate the stem cell niche and stem cell proliferation, expansion, and differentiation [ 52 , 53 , 54 ]. Smadja et al found that WNT antagonists enhance the proliferation of ECFCs and their capacity to differentiate [ 55 ].…”

Section: Signaling Pathways Driven By and Affecting Epcsmentioning

confidence: 99%

The State of Art of Regenerative Therapy in Cardiovascular Ischemic Disease: Biology, Signaling Pathways, and Epigenetics of Endothelial Progenitor Cells

Perrotta

Perna

Komici

et al. 2020

Cells

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Ischemic heart disease is currently a major cause of mortality and morbidity worldwide. Nevertheless, the actual therapeutic scenario does not target myocardial cell regeneration and consequently, the progression toward the late stage of chronic heart failure is common. Endothelial progenitor cells (EPCs) are bone marrow-derived stem cells that contribute to the homeostasis of the endothelial wall in acute and chronic ischemic disease. Calcium modulation and other molecular pathways (NOTCH, VEGFR, and CXCR4) contribute to EPC proliferation and differentiation. The present review provides a summary of EPC biology with a particular focus on the regulatory pathways of EPCs and describes promising applications for cardiovascular cell therapy.

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Effects of curcumin and its adjuvant on TPC1 thyroid cell line

Cited by 32 publications

References 38 publications

Curcumin as an Anticancer Agent in Malignant Mesothelioma: A Review

Curcumin as an Anticancer Agent in Malignant Mesothelioma: A Review

Nutraceuticals in Thyroidology: A Review of in Vitro, and in Vivo Animal Studies

The State of Art of Regenerative Therapy in Cardiovascular Ischemic Disease: Biology, Signaling Pathways, and Epigenetics of Endothelial Progenitor Cells

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