Effects of Curcuma longa on the intestinal health of chicks infected with Salmonella Typhimurium

Abstract

Non-ruminants Full-length research article Effects of Curcuma longa on the intestinal health of chicks infected with Salmonella Typhimurium ABSTRACT-This study was conducted to evaluate the effects of Curcuma longa on the growth performance, intestinal integrity, and antimicrobial activity of chicks colonized by Salmonella Typhimurium. The study included 672 one-day-old male chicks of the Cobb TM lineage, which were divided into eight treatment groups with 14 birds per group and six repetitions, for a total of 48 experimental units per treatment. A randomized 4×2 factorial design scheme (C. longa levels × inoculation by Salmonella Typhimurium) was used. Chicks were orally inoculated with 1.2×10 4 cfu/mL of Salmonella Typhimurium in 0.5 mL of 0.85% buffered saline solution. Curcuma was added to the feed of chicks at 0, 1, 2, and 3% for 35 days. Data were analyzed by analysis of variance and Tukey's test. Optimal feed conversion was observed in chicks given feed supplemented with 1% C. longa, regardless of infection, and 1% C. longa prevented intestinal colonization by Salmonella Typhimurium. Supplementation and bacterial infection influenced the histomorphometry and pH of the intestine. Bacterial infection reduced the intestinal pH, whereas C. longa supplementation increased the pH, but only in infected chicks. Thus, supplementation with 1% C. longa favors feed conversion, inhibits intestinal colonization by Salmonella Typhimurium, and does not alter intestinal integrity. In contrast, supplementation with 3% Curcuma longa decreases feed intake, affecting the performance of 35-day-old chicks.

Advances in enteropathogen control throughout the meat chicken production chain

“…Feed 4 (Ahmed & Yang, 2017;Islam et al, 2016;Kumar et al, 2017;Nascimento et al, 2019) 1 (Sadeghi et al, 2013) N / A Active ingredient Feed 7 (Amerah et al, 2012;Hernandez-Patlan et al, 2018;Kollanoor-Johny, Mattson, Baskaran, Amalaradjou, Babapoor, et al, 2012;Kollanoor-Johny, Upadhyay, et al, 2012;Peinado et al, 2012;Wang et al, 2018;Wu et al, 2018) 4 (Cerisuelo et al, 2014;do Amaral et al, 2016;Hoffman-Pennesi & Wu, 2010;Zhang et al, 2017) Enviva R EO 101 (Amerah et al, 2012) Cerisuelo et al, 2014;Gao et al, 2019;Grilli et al, 2011;Hassan et al, 2010;Hernandez-Patlan, Solis-Cruz, Pontin, et al, 2019;Hernandez-Patlan et al, 2018;Machado et al, 2014;Natsir et al, 2017;Pathak et al, 2017) 0 A m a r i l R (Pathak et al, 2017), FormaXOL R (Abudabos et al, 2014), Biacid™ (Hassan et al, 2010), Oregain R Water 2 Machado et al, 2014) 0…”

“…Other phytogenic additives that may reduce Salmonella are quercetin (Soleimani, Zulkifli, Hair‐Bejo, Omar, et al., 2012; Wang et al., 2018), ginger root extract (Ofongo‐Abule & Ohimain, 2015), sanguinarine (Pickler et al., 2013), oridonin (Wu et al., 2018), curcumin (Hernandez‐Patlan et al., 2018; Hernandez‐Patlan, Solis‐Cruz, Pontin, et al., 2019), tetramethylpyrazine (Liu, Lin, et al., 2019; Liu, Wang, et al., 2018), pine bark extract (Park, 2011), Achyranthes japonica extract (Park & Kim, 2020), turmeric (Nascimento et al., 2019), pomegranate byproducts (Ahmed & Yang, 2017), mushroom extract (Willis et al., 2009), and black cumin seeds (Islam et al., 2016; Kumar et al., 2017). Some other phytogenic additives that may reduce Campylobacter are terpenoid compounds (Kurekci et al., 2014), β‐resorcylic acid (Wagle, Upadhyay, et al., 2017), Galla rhois and Cinnamomum cassia extracts (Cho et al., 2016), propyl propane thiosulfonate (Peinado et al., 2012), seaweed extract (Sweeney et al., 2016), and olive mill wastewater extract (Branciari et al., 2016).…”

Advances in Enteropathogen Control Throughout the Meat Chicken Production Chain

“…By-product 2 [191,192] 0 0 Active ingredient 5 [193][194][195][196][197] 0 1 [198] Extract 3 [135,147,195] 2 [199,200] 0 Excential Alliin Plus[135] Combination treatments 5 [133,135,[147][148][149] 1 [150] 0 Biotronic® Top3 [135], Power Protexion [135], Anta®Phyt [135] Feed and water additives containing phenolic compounds were seen to reduce Salmonella [164,166,167,181,183,184] or Campylobacter [193,196,197,199] in numerous studies. Other phytogenic additives that may reduce Salmonella are quercetin [169,201], ginger root extract [185], sanguinarine [173], oridonin [170], curcumin [165,186], tetramethylpyrazine [202,203], pine bark extract [177], Achyranthes japonica extract [178], turmeric [162], pomegranate by-products …”

Pathology and Public Health Significance of Salmonella

“…Salmonella disease in calves prompts fever and looseness of the bowels, with high mortality if no anti-toxin treatment is given (Birhanu et al 2018). S. typhimurium contamination in day-old chicks additionally prompts enteric and other fundamental illnesses, with a high death rate (Nascimento et al 2019), while disease in more seasoned chicks prompts asymptomatic colonization of dung with relentless discharge of living organisms in defecation (Deng et al 2020). S. enterica subspecies enteric serotype typhimurium (S. typhimurium) is perceived as a human microorganism and represents a sanitation hazard around the world.…”