“…In the areas where the plant grows, its fruit is traditionally used orally and topically for the treatment of various diseases such as sinusitis, fever, cancer, hepatic diseases, jaundice, constipation, hypertension, edema, rheumatic diseases and fungous infections [1][2][3]. Pharmacological studies have demonstrated that the plant's fruit has anticancer [4][5][6], antibacterial [3], antifungal [3], analgesic [7], antipyretic [7], anti-inflammatory [8], positive inotropic [9], hepatoprotective [10], blood bilirubin reducing [11], anti-leukemic [12] and anti-sinusitis [13,14] effects, among others. The plant contains many bioactive compounds including phenols, flavonoids such as rutin (phytomelin) and triterpenoids (cucurbitacins) [15].…”