Effects of Continuous Positive Airway Pressure (CPAP) Used for Respiratory Motion Management in Patients Receiving Chest Radiation to the Heart: An Analysis of Size, Position, and Motion

Abstract

Materials/Methods: The appropriate anatomical structures were identified in a 3T MR sequence. Prescription doses and target selection for each treatment type were identified from previously published work. GK treatment was simulated with 4-or 8-mm collimator. VMAT treatment was simulated using MLC-based virtual cone approach previously developed to replicate spherical GK dose profile. Plans were reviewed for acceptability by the multidisciplinary team. Gradient, V12Gy, and mean brain dose were compared for each case between the 2 delivery systems. Results: For each case, the linear accelerator approach was able to generate a plan nearly dosimetrically equivalent to its GK counterpart, and to metrics previously reported in the literature. Individual plan quality metrics are provided in Table 1. Conclusion: Coneless MLC-based VMAT on the linear accelerator is a feasible option for SRS of functional neurological conditions.