Effects of contiguous scars in dermatoscopic evaluation of clinically atypical melanocytic nevi

The role of antinuclear autoantibodies in patients with psoriasis treated with anti–tumor necrosis factor-alpha agents: A retrospective long-term study

“…Therefore the inhibition of TNF-a possibly induces IFN-a production by pDCs, which lead to a psoriasiform eruption and pustular dermatisis. 4,5 In our study, the serum concentration of chemerin was elevated, whereas serum IL-17 level was within a normal range. This result suggests that chemerin plays an important role in the formation of pustular dermatitis caused by the TNF-a inhibitor, although we currently cannot propose the exact mechanism underlying the chemerin elevation by etanercept.…”

Recurrent Melanocytic Nevi and Melanomas in Dermoscopy

“…It is precisely this question that the present IDS study was designed to answer. 15 Besides case reports [8][9][10][11][12][13] the largest study on this subject was performed by Botella-Estrada et al 14 They analyzed clinical and dermoscopic features of 57 recurrent melanocytic tumors with a classification into 4 categories: reactive pigmented scar with macular, banded, or diffuse pigmentation (72.6%); recurrent nevus (24.2%); recurrent melanoma (1.1%); and metastatic melanomas (2.1%). In the histopathologic examination, 56.1% were classified as reactive hyperpigmentation; 38.6% were recurrent nevi; 1.8%, recurrent; and 3.5%, metastatic melanoma.…”

“…Some of these observations have been described previously in a few case reports. [8][9][10][11][12][13] The presence of circles is closely linked to the anatomic location of the lesion; they are more commonly found in recurrent melanoma of the face (65.5%) than in recurrent melanoma on other body areas (6.1%). Unfortunately, the number of cases in this study precluded us from stratifying the data based on location.…”

“…Numerous case reports have been published. [8][9][10][11][12][13] Botella-Estrada et al 14 performed the largest study and analyzed the clinical, dermoscopic, and histopathologic characteristics of 57 recurrent melanocytic lesions. To obtain a larger number of cases, the International Dermoscopy Society (IDS) launched a multicenter retrospective, observational study to determine dermoscopic characteristics to differentiate recurrent nevi from recurrent melanomas.…”