“…These detrimental blood flow changes affect skin breakdown in multiple ways, [7][8] with the greatest frequency at sites of bony prominences. The heel is particularly prone to such effects, 9 in part because of its relatively lower resting blood perfusion level, 10 higher amounts of surface pressure when under load, [11][12][13][14] and the possibility of compromised local blood flow if lower-extremity arterial disease is present. 10 Skin breakdown processes are affected by decreases in local blood flow during heel loading 10 and by flow recovery features after unloading.…”