Effects of common lifestyle factors on obstructive sleep apnea: precautions in daily life based on causal inferences
Kun Liu,
Chenyang Zang,
Jixu Wang
et al.
Abstract:BackgroundThis study aimed to evaluate the causal impact of common modifiable lifestyles on obstructive sleep apnea (OSA), which is beneficial for recommendations to prevent and manage OSA.MethodPublished genome-wide association study (GWAS) summary statistics were used to perform two-sample Mendelian randomization (MR). Variants associated with each exposure of smoking, drinking, and leisure sedentary behaviors at the genetic level were used as instrumental variables (IVs). Then, inverse-variance weighting (I… Show more
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