“…Three studies in rodent models found that the adverse effects of PB were enhanced by stressors ( Abdel-Rahman, Abou-Donia, El-Masry, Shetty, & Abou-Donia, 2004 ; Abdel-Rahman, Shetty, & Abou-Donia, 2002 ; Friedman et al, 1996 ). Other studies showed reduced levels of acetylcholin-esterase (AChE) in the brains of animals given PB and exposed to stressors ( Baireddy, Mirajkar, Nallapaneni, Singleton, & Pope, 2007 ; Sinton, Fitch, Petty, & Haley, 2000 ). PB administered with the nerve agent sarin produced locomotor deficits ( Abou-Donia et al, 2002 ; Scremin et al, 2003 ), EEG abnormalities ( van Helden et al, 2004 ), changes in HRV ( Scremin et al, 2003 ) and increased markers of oxidative stress in urine ( Shih, Hulet, & McDonough, 2006 ).…”