Effects of collection time on the antimicrobial activities of Harpephyllum caffrum bark

Buwa, L.V.; Staden, J. Van

doi:10.1016/j.sajb.2006.09.006

Cited by 14 publications

(6 citation statements)

References 23 publications

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“…The ethanolic extract of H. caffrum was reported to be active against four bacterial species, namely Bacillus subtilis, E. coli, Klebsiella pneumoniae and S. aureus, while an aqueous extract showed activity against C. albicans. 47 The acetone extracts of the bark and leaves of S. birrea were reported to be active against S. aureus, P. aeruginosa, E. coli and Enterococcus faecalis at MIC values ranging from 150 µg/mL to 3000 µg/mL. 48 In a study done by Motsei et al 49 52 , the DPPH radical scavenging activity of A. linearis and its constituents were confirmed.…”

Section: Discussionmentioning

confidence: 94%

Antibacterial, antioxidant activities and cytotoxicity of plants against Propionibacterium acnes

Sharma

Lall

2014

S. Afr. J. Sci.

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The use of plants to treat skin ailments has strong support in the current trend of drug discovery. Propionibacterium acnes, an anaerobic pathogen, plays an important role in the occurrence of acne. The present study was conducted to evaluate the antimicrobial and antioxidant activities against P. acnes and cytotoxic effects of 48 medicinal plants grown in South Africa. The broth dilution and DPPH radical scavenging methods were used to determine antibacterial and antioxidant activities, respectively. Cytotoxicity was determined on mouse melanocytes (B16-F10). The ethanolic bark extract of Acacia galpinii Burtt Davy. (Leguminosae) exhibited the lowest minimum inhibitory concentration of 62.5 µg/mL. Excellent antioxidant activity was shown by Aspalathus linearis (Burm.f.) R.Dahlgren (Leguminosae), Combretum apiculatum Sond. (Combretaceae), Harpephyllum caffrum Bernh. ex Krauss (Anacardiaceae) and Sclerocarya birrea Hochst. (Anacardiaceae), with 50% radical scavenging activity (EC 50 ) at concentrations ranging from 1.6 µg/mL to 3.5 µg/mL. Greyia sutherlandii Hook. & Harv. (Greyiaceae) also exhibited good antioxidant activity with an EC 50 value of 7.9±0.23 µg/mL. A. linearis, G. sutherlandii and S. birrea showed low toxicity with 50% viability of cells (EC 50 ) at concentrations of 125.09±0.71 µg/mL, 107.85±1.53 µg/mL and 92.07±0.09 µg/mL, respectively. The extracts of A. linearis, G. sutherlandii and S. birrea showed good antibacterial and antioxidant activities and low toxicity. Therefore, these plants can be considered as possible anti-acne agents and warrant further investigation.

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Section: Discussionmentioning

confidence: 94%

Antibacterial, antioxidant activities and cytotoxicity of plants against Propionibacterium acnes

Sharma

Lall

2014

S. Afr. J. Sci.

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“…Seasonal variation studies on bark extracts of Harpephyllum caffrum demonstrated little antimicrobial variability between the months June 2003 and September 2004 (Buwa and Van Staden, 2007).…”

Section: Antimicrobial Investigation On Extractsmentioning

confidence: 98%

Antimicrobial activity of South African medicinal plants

Vuuren

2008

Journal of Ethnopharmacology

225

182

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“…No study has been conducted to assess the effect of seasonal change on Nigerian medicinal plants. South African studies reported little antimicrobial variability of plant extracts within 2 months interval [ 16 , 193 ]. Some papers on Nigerian plants focused on the antimicrobial screening together with other pharmacological investigations including toxicity [ 18 , 42 , 54 , 60 , 85 , 95 , 120 , 191 , 194 , 195 ].…”

Section: Antimicrobial Investigation On Nigerian Plant Extractsmentioning

confidence: 99%

Antimicrobial activity of Nigerian medicinal plants

Anyanwu¹,

Okoye²

2017

J Intercult Ethnopharmacol

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Antimicrobial resistance (AMR) is currently one of the major threats facing mankind. The emergence and rapid spread of multi- and pan-drug-resistant organisms (such as vancomycin-, methicillin-, extended-spectrum β-lactam-, carbapenem- and colistin-resistant organisms) has put the world in a dilemma. The health and economic burden associated with AMR on a global scale are dreadful. Available antimicrobials have been misused and are almost ineffective with some of these drugs associated with dangerous side effects in some individuals. Development of new, effective, and safe antimicrobials is one of the ways by which AMR burden can be reduced. The rate at which microorganisms develop AMR mechanisms outpaces the rate at which new antimicrobials are being developed. Medicinal plants are potential sources of new antimicrobial molecules. There is renewed interest in antimicrobial activities of phytochemicals. Nigeria boasts of a huge heritage of medicinal plants and there is avalanche of researches that have been undertaken to screen antimicrobial activities of these plants. Scientific compilation of these studies could provide useful information on the antimicrobial properties of the plants. This information can be useful in the development of new antimicrobial drugs. This paper reviews antimicrobial researches that have been undertaken on Nigerian medicinal plants.

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Effects of collection time on the antimicrobial activities of Harpephyllum caffrum bark

Cited by 14 publications

References 23 publications

Antibacterial, antioxidant activities and cytotoxicity of plants against Propionibacterium acnes

Antibacterial, antioxidant activities and cytotoxicity of plants against Propionibacterium acnes

Antimicrobial activity of South African medicinal plants

Antimicrobial activity of Nigerian medicinal plants

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