Effects of Climate Change on Geotechnical Infrastructures — state of the art

Kandalai, Srikanth; John, Nithin Jacob; Patel, Anjan

doi:10.1007/s11356-022-24788-7

Cited by 10 publications

(2 citation statements)

References 180 publications

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“…[4,50,61] The roles of nitric oxide (NO) and MDA in the pathogenesis of either IBD or seizures have been documented. [62][63][64] However, it remains unclear whether these factors also contribute to the concurrent occurrence of these diseases. Findings of the present study showed that, partially at least, a decrease in latency to seizure in colitis is associated with an increase in MDA and NO levels as well as a reduction in TAC in the PFC and colon samples.…”

Section: Microscopic Assessment Of the Effects Of Colitis And Seizure...mentioning

confidence: 99%

Neuroimmune response and oxidative stress in the prefrontal cortex mediate seizure susceptibility in experimental colitis in male mice

Moradipoor,

Jivad,

Asgharzadeh

et al. 2024

J Biochem & Molecular Tox

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Inflammatory bowel disease (IBD) is a chronic gastrointestinal disorder. Oxidative stress and inflammatory responses have a vital role in the pathophysiology of IBD as well as seizure. IBD is associated with extraintestinal manifestations. This study aimed to explore the relationship between colitis and susceptibility to seizures, with a focus on the roles of neuroinflammation and oxidative stress in acetic acid‐induced colitis in mice. Forty male Naval Medical Research Institute mice were divided into four groups: control, colitis, pentylenetetrazole (PTZ), and colitis + PTZ. Colitis was induced by intrarectal administration of acetic acid, and seizures were induced by intravenous injection of PTZ 7 days postcolitis induction. Following the measurement of latency to seizure, the mice were killed, and their colons and prefrontal cortex (PFC) were dissected. Gene expression of inflammatory markers including interleukin‐1β, tumor necrosis factor‐alpha, NOD‐like receptor protein 3, and toll‐like receptor 4, as well as total antioxidant capacity (TAC), malondialdehyde (MDA), and nitrite levels were measured in the colon and PFC. Histopathological evaluations were performed on the colon samples. Data were analyzed by t‐test or one‐way variance analysis. Colitis decreased latency to seizure, increased gene expression of inflammatory markers, and altered levels of MDA, nitrite, and TAC in both the colon and PFC. Simultaneous induction of colitis and seizure exacerbated the neuroimmune response and oxidative stress in the PFC and colon. Results concluded that neuroinflammation and oxidative stress in the PFC at least partially mediate the comorbid decrease in seizure latency in mice with colitis.

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Section: Microscopic Assessment Of the Effects Of Colitis And Seizure...mentioning

confidence: 99%

Neuroimmune response and oxidative stress in the prefrontal cortex mediate seizure susceptibility in experimental colitis in male mice

Moradipoor,

Jivad,

Asgharzadeh

et al. 2024

J Biochem & Molecular Tox

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“…The adverse effects of drying cracks on the mechanical properties, stability, and structure of the soil, as well as the dynamics of surface runoff, groundwater recharge, infiltration, and permeability, have been investigated in several studies [1][2][3]. These changes result in issues such as differential settlement, a reduced soil-bearing capacity, landslides, erosion, and infiltration into water reservoirs or waste deposits [4,5]. While traditional methods of reducing the cracking potential of soils using chemical agents such as lime and Portland cement are well documented, recent efforts in line with the Sustainable Development Goals (SDGs) [6], based on the use of recycled waste for soil strengthening, are in their early stages.…”

Section: Introductionmentioning

confidence: 99%

Use of Recycled Plastic Fibers to Control Shrinkage and Desiccation Cracking in Clayey Soils

Hernández,

Beltrán,

Botero

2024

Sustainability

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Two main issues are addressed in this work. The first issue is environmental concerns about managing plastic waste on a large scale by promoting reuse with low energy requirements in the recycling processes. The second issue is the desiccation cracks in fine soils, induced by prolonged droughts, which have motivated the interest in mitigating the adverse effects on the stability of geotechnical works using recycled materials. Therefore, this work addresses a strategy based on the use of recycled polyethylene terephthalate (PET) and polypropylene (PP) fibers for the reinforcement of soils prone to cracking. To evaluate the effectiveness of plastic fibers in controlling soil volumetric changes and cracking during drying, several experiments were conducted in an environmental chamber to properly simulate and monitor the desiccation process. Image analysis and suction measurements provided several metrics and parameters, and their usefulness is discussed in detail, both for the unconventional determination of the optimum fiber content by weight with 100% effectiveness in preventing cracking and for correlating fiber content with reductions in shrinkage and cracking patterns, thus contributing to the understanding of the behavior of fiber-reinforced soils. Finally, examples of large-scale applications of recycled plastic fibers in geotechnical works are proposed, and the positive environmental impact is estimated.

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Climate-Related Financial Regulations and their Impact on Geotechnical Engineering

Firoozi,

Firoozi

2024

Sustainable Finance

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Effects of Climate Change on Geotechnical Infrastructures — state of the art

Cited by 10 publications

References 180 publications

Neuroimmune response and oxidative stress in the prefrontal cortex mediate seizure susceptibility in experimental colitis in male mice

Neuroimmune response and oxidative stress in the prefrontal cortex mediate seizure susceptibility in experimental colitis in male mice

Use of Recycled Plastic Fibers to Control Shrinkage and Desiccation Cracking in Clayey Soils

Climate-Related Financial Regulations and their Impact on Geotechnical Engineering

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