“…Tobacco smoking is the leading cause of preventable disease (Samet, 2013) and individuals with elevated depression symptoms are more likely to initiate smoking and have a harder time quitting smoking (Fluharty, Taylor, Grabski, & Munafò, 2017;Pang, Farrahi, Glazier, Sussman, & Leventhal, 2014). High negative affect and low positive affect are core symptoms of depression (Mathew, Hogarth, Leventhal, Cook, & Hitsman, 2017) and are prominent symptoms following cigarette abstinence (Klemperer, et al, 2021;Pang, Chai, et al, 2022). Investigating associations of biological markers with affect may provide valuable information about factors relevant to smoking cessation in individuals with elevated depression symptoms.…”