Effects of chronic ethanol consumption on lactational performance in rat: Mammary gland and milk composition and pups' growth and metabolism

Vilaró, Senén; Viñas, Octavi; Remesar, Xavier; Herrera, Emílio

doi:10.1016/0091-3057(87)90577-6

Cited by 69 publications

(57 citation statements)

References 28 publications

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“…Moreover, ethanol consumption may alter the composition of milk such that, although infants are consuming less milk, they are taking in the same amount of calories. Chronic ethanol consumption by lactating rat dams during both pregnancy and lactation resulted in the production of a milk that was higher in lipid and lower in lactose content, when compared to the milk of control rat dams (Vilaró, Viñas, Remesar, & Herrera, 1987). Because no alteration in protein or water content was observed, the milk of ethanol-exposed rats had a higher energy content due to the greater energetic value of lipids compared to proteins and lactose.…”

Section: Discussionmentioning

confidence: 95%

Beer, breast feeding, and folklore

Mennella

Beauchamp

1993

Developmental Psychobiology

123

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Beer consumption by nursing women altered the sensory qualities of their milk and the behavior of their infants during breast-feeding in the short term. The infants consumed significantly less milk during the 4-hr testing sessions in which their mothers drank alcoholic beer compared to when the mothers drank nonalcoholic beer; this decrease in milk intake was not due to a decrease in the number of times the babies fed. Although the infants consumed less of the alcohol-flavored milk, the mothers believed their infants had ingested enough milk, reported that they experienced a letdown during nursing, and felt they had milk remaining in their breasts at the end of the majority of feedings. Moreover, the mothers terminated the feeds the same percentage of time on both testing days. The mechanism by which the consumption of alcoholic beer by lactating women decreases milk intake by their nurslings remains to be determined.

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Section: Discussionmentioning

confidence: 95%

Beer, breast feeding, and folklore

Mennella

Beauchamp

1993

Developmental Psychobiology

123

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“…For example, an ethanol dose of .1?0 g/kg significantly inhibited milk-ejecting activities (measured via intra-mammary and intra-uterine pressure changes) and the inhibition correlated with administered ethanol dose more closely than with blood ethanol levels (23) . Studies have also demonstrated that suckling-induced oxytocin levels are attenuated following ethanol consumption in non-lactating women (22) and lactating rats (17)(18)(19)(20)(21) . Similarly, the present study found a statistically significant increase ( , 52 %, 4?4 v. 2?9 min, P , 0?05) in the time for ejection of the first milk droplet in the exposed (CSSR) group in comparison with the non-alcoholic diet group.…”

Section: Influence Of Alcoholic Diet On Milk Compositionmentioning

confidence: 99%

Maternal lactation characteristics after consumption of an alcoholic soup during the postpartum ‘doing-the-month’ ritual

Chien

Huang

Hsu

et al. 2008

PHN

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Objective: The present study examined whether ethanol exposure influences lactation parameters. Specifically, selected constituents in maternal blood and milk and the lactation performance of Chinese lactating mothers were evaluated after they had consumed chicken soup flavoured with sesame oil and rice wine (CSSR), a diet traditionally prescribed during the postpartum 'doing-the-month' ritual. Design: Twenty-three lactating mothers were examined. Informed consent was obtained from each subject. Each subject was tested on two occasions separated by a week. The target alcohol dosage was 0?3 g/kg body weight. Milk and blood samples were collected prior to consumption of soup and at 120 and 150 min, respectively, after consumption. Levels of various constituents were measured. The time for ejection of the first milk droplet and total milk volume yielded were also measured. Results: Consumption of CSSR influenced TAG, insulin and lactate levels in maternal blood. Likewise, consumption of the soup affected milk composition and its nutritional status, particularly total protein, TAG, fatty acid, b-hydroxybutyrate and lactate levels. CSSR intake significantly affected TAG and lactate levels in milk. The time for the first milk droplet to be ejected was significantly longer in the CSSR group, indicating that the milk-ejecting reflex is inhibited. However, blood prolactin level increased slightly after ethanol intake. Milk yields were reduced after ingestion of CSSR although the difference was not statistically significant. Conclusion: Consumption of CSSR affects not only the composition of maternal blood and milk, but also lactation performance. These findings suggest that an alcoholic diet should be avoided during lactation.

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“…49 This decrease is associated with reduced milk production in the alcohol-fed dams despite their milk having a higher energy content due to a greater lipid concentration.…”

Section: Growth Indicesmentioning

confidence: 99%

“…It is known that the lipid content increases in the milk of alcohol-treated rats. 49 This high lipid content partially compensates for the alcohol-induced malnutrition occurring in the alcohol-exposed pups and allows the proper metabolic adaptations to prevent severe hypoglycaemia and maintain minimum liver stores of glycogen. However, these adaptations are not enough to protect against impaired brain development, evident in the alcohol-exposed pups.…”

Section: Growth Indicesmentioning

confidence: 99%

Alcohol and lactation: A systematic review

Giglia

Binns

2006

Nutrition & Dietetics

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The aim of the present paper is to critically review the current literature on the effect of alcohol intake during lactation on the hormonal control of lactogenesis; breast milk and infant blood alcohol concentration; and on the breastfeeding infant. The databases PubMed, CINAHL, Proquest Health and Medical Complete, ScienceDirect and ISI Web of Knowledge were searched for articles published between 1990 and 2005. We found limited research investigating the effect of alcohol intake on the infants of lactating women, with most being conducted using animal models. Results consistently show a decrease in lactational performance in both animal and human studies of alcohol intake and breastfeeding. Alcohol intake by lactating mothers in amounts recommended as 'safe' for nonlactating women may have a negative effect on infant development and behaviour. Clear guidelines for alcohol consumption are required for lactating women and health professionals to guide breastfeeding mothers to make educated choices regarding alcohol intake during this critical period of infant development.

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Effects of chronic ethanol consumption on lactational performance in rat: Mammary gland and milk composition and pups' growth and metabolism

Cited by 69 publications

References 28 publications

Beer, breast feeding, and folklore

Beer, breast feeding, and folklore

Maternal lactation characteristics after consumption of an alcoholic soup during the postpartum ‘doing-the-month’ ritual

Alcohol and lactation: A systematic review

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