Effects of chronic consumption of metanil yellow by developing and adult rats on brain regional levels of noradrenaline, dopamine and serotonin, on acetylcholine esterase activity and on operant conditioning

Tirumuru, Nagaraja; Desiraju, T.

doi:10.1016/0278-6915(93)90177-z

Cited by 65 publications

(43 citation statements)

References 8 publications

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“…Metanil Yellow, Allura Red (red 40), Auramine O and Orange II are among the most hazardous synthetic food colors used in food to affect human health. The dye Metanil Yellow affects the central nervous system (CNS) to cause neurotoxicity (Nagaraja and Desiraju (1993); Allura red causes chromosomal damage and introduces hyperactivity and lymphoma cancer (Tanaka 1994).…”

Section: Introductionmentioning

confidence: 99%

Nanocarbon–{[Na10(PrW10O36)]2·130H2O} composite to detect toxic food coloring dyes at nanolevel

Dutta

Sarkar

2016

Appl Nanosci

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Monitoring of adulterated and toxic food colors is important due to their potential toxicity and pathogenicity. Here, we repot an Ln-POM (lanthanide polyoxometalate) cluster, {[Na 10 (PrW 10 O 36 )] 2 Á130H 2 O}, with carbon nano-onion (CNO) hybrid composite which is a highly efficient sensor for the rapid detection of toxic dyes like metanil yellow, auramine O, Orange II and in allura red (red 40) as low as 3.83; 4.73; 4.14 and 2.90 nmol ml -1 concentration, respectively, by fluorescence spectroscopy.

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Section: Introductionmentioning

confidence: 99%

Nanocarbon–{[Na10(PrW10O36)]2·130H2O} composite to detect toxic food coloring dyes at nanolevel

Dutta

Sarkar

2016

Appl Nanosci

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“…Toxicologically, metanil yellow is classified as a CII category substance by the Joint Food and Agricultural Organization of the United Nations (FAO) and World Health Organization (WHO) expert committee on Food Additives [61]. Study on rats shows that the consumption of metanil yellow causes neurotoxicity [62], hepatocellular carcinoma [63], tumor development [64], deleterious effect on gastric mucin [65], and lymphocytic leukemia [66]. This study demonstrates the application of the 1064 nm dispersive Raman spectral imaging system for the detection of metanil yellow contamination in turmeric powder and subsurface detection and identification of gelatin-encapsulated pure and mixed samples of metanil yellow and turmeric powder.…”

Section: Application To Authenticate Turmeric Powdermentioning

confidence: 99%

A 1064 nm Dispersive Raman Spectral Imaging System for Food Safety and Quality Evaluation

et al. 2018

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Raman spectral imaging is an effective method to analyze and evaluate the chemical composition and structure of a sample, and has many applications for food safety and quality research. This study developed a 1064 nm dispersive Raman spectral imaging system for surface and subsurface analysis of food samples. A 1064 nm laser module is used for sample excitation. A bifurcated optical fiber coupled with Raman probe is used to focus excitation laser on the sample and carry scattering signal to the spectrograph. A high throughput volume phase grating disperses the incoming Raman signal. A 512 pixels Indium-Gallium-Arsenide (InGaAs) detector receives the dispersed light signal. A motorized positioning table moves the sample in two-axis directions, accumulating hyperspectral image of the sample by the point-scan method. An interface software was developed in-house for parameterization, data acquisition, and data transfer. The system was spectrally calibrated using naphthalene and polystyrene. It has the Raman shift range of 142 to 1820 cm −1 , the spectral resolution of 12 cm −1 at full width half maximum (FWHM). The spatial resolution of the system was evaluated using a standard resolution glass test chart. It has the spatial resolution of 0.1 mm. The application of the system was demonstrated by surface and subsurface detection of metanil yellow contamination in turmeric powder. Results indicate that the 1064 nm dispersive Raman spectral imaging system is a useful tool for food safety and quality evaluation.

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“…These interactions are a potential health risk, especially when they are consumed excessively [51]. There have been various studies focused on neurotoxicity [54], genotoxicity [53] and carcinogenicity [41] of synthetic dyes. The relationship between dyes and the children´s attention deficit disorder (ADD), attention-deficit hyperactivity disorder (ADHD), immune system problems, and certain allergic reactions have also been examined.…”

Section: Introductionmentioning

confidence: 99%

Organic Colouring Agents in the Pharmaceutical Industry

et al. 2017

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Effects of chronic consumption of metanil yellow by developing and adult rats on brain regional levels of noradrenaline, dopamine and serotonin, on acetylcholine esterase activity and on operant conditioning

Cited by 65 publications

References 8 publications

Nanocarbon–{[Na10(PrW10O36)]2·130H2O} composite to detect toxic food coloring dyes at nanolevel

Nanocarbon–{[Na10(PrW10O36)]2·130H2O} composite to detect toxic food coloring dyes at nanolevel

A 1064 nm Dispersive Raman Spectral Imaging System for Food Safety and Quality Evaluation

Organic Colouring Agents in the Pharmaceutical Industry

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