Effects of changes in intravascular oncotic pressure on renal responses to volume loading in the saltwater-acclimated Pekin duck (Anas platyrhynchos)

Keil, R.; Gerstberger, Rüdiger; Simón, E.

doi:10.1007/bf00262882

Cited by 8 publications

(1 citation statement)

References 36 publications

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“…The main finding of this study was that although ANP is present in duck urine, the infusion of the peptide in amounts that produced physiological increases in its plasma concentration (Keil et al 1991) -which were associated with natriuresis and diuresis, caused no change in the urinary concentration and excretion of ANP. There was no correlation between the urine and plasma levels of ANP under these experimental conditions, with the urinary concentration remaining relatively constant de¬ spite the marked elevations in blood concentration.…”

Section: Discussionmentioning

confidence: 95%

Urinary clearance of atrial natriuretic peptide in Pekin ducks

Gray

1995

Journal of Endocrinology

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To quantify the renal excretion of atrial natriuretic peptide (ANP) in birds, synthetic ANP was infused intravenously into conscious Pekin ducks at rates of 10, 30 and 90 ng/kg per min for 30 min and the relationships between plasma and urine ANP concentrations were monitored by RIA. The infusions of ANP produced dose-dependent elevations in the plasma concentrations of the hormone; however, urinary concentrations and excretion rates did not change significantly from the basal values of 142.2 +/- 21.5 pg/ml and 26.4 +/- 4.5 pg/min per kg respectively. The metabolic clearance rate of ANP remained constant at each infusion dose (approximately 200 ml/min per kg). The urinary clearance rates (< 0.3 ml/min per kg) indicated that the fraction of ANP cleared from the blood via the urine was less than 0.2%. Clearly, excretion of intact ANP via this route is not a quantitatively important means of elimination for this hormone in birds.

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Section: Discussionmentioning

confidence: 95%