Effects of certain stress factors on the re-excretion of infectious laryngotracheitis virus from latently infected carrier birds

Hughes, Carolyn S.; Gaskell, Rosalind M.; Jones, Richard C.; Bradbury, Janet M.; Jordan, F. T. W.

doi:10.1016/s0034-5288(18)31158-5

Cited by 88 publications

(51 citation statements)

References 13 publications

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“…Natural stress factors including re-housing, mixing and the onset of lay are recognised factors that will trigger recrudescence and shedding of latent virus (Hughes et al, 1989). Initial epidemiological investigations on the index site indicated that the first affected house comprised 5,000 vaccinated and 15,000 unvaccinated point of lay birds recently imported from England.…”

Section: Discussionmentioning

confidence: 99%

RFLP analysis of recent Northern Ireland isolates of infectious laryngotracheitis virus: Comparison with vaccine virus and field isolates from England, Scotland and the Republic of Ireland

Graham¹,

McLaren²,

Calvert³

et al. 2000

Avian Pathology

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Restriction fragment length polymorphism (RFLP) analysis was used to assist epidemiological investigations following the recent introduction of infectious laryngotracheitis virus (ILTV) to commercial poultry flocks in Northern Ireland (NI). A 4.9 kbp PCR product of the ILTV ICP4 gene was generated from each of 16 field isolates of ILTV originating from England, Scotland, NI and the Republic of Ireland (RoI) and of the single vaccine strain currently licenced for use within the United Kingdom. With the exception of isolate PV6/94 from RoI, all field isolates generated RFLP patterns, following digestion with HaeIII, similar to that obtained using the vaccinal strain. Following MspI digestion, NI isolates were indistinguishable from the vaccinal strain and recent English isolates. However, one English and one Scottish isolate, both made prior to the introduction of vaccination, and two isolates from RoI generated a second pattern following digestion with MspI.

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Section: Discussionmentioning

confidence: 99%

RFLP analysis of recent Northern Ireland isolates of infectious laryngotracheitis virus: Comparison with vaccine virus and field isolates from England, Scotland and the Republic of Ireland

Graham¹,

McLaren²,

Calvert³

et al. 2000

Avian Pathology

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“…Accordingly, the necrosis of blood vessels may lead to ischaemic damage which in turn induces a necrotizing process with more expression of phosphorylated protein. The state of herpesvirus latency can be overcome in vitro by chemical induction with IUdR or other agents (Decaussin et al, 1995;Dunn & Nazerian, 1977;Ikuta et al, 1985;Kirchner et al, 1991;Nakajima et al, 1987;Ono et al, 1984) and in vivo by induction of immune deficiency (Croen, 1991) or certain stresses (Hughes et al, 1989). Cell-mediated immunity is important in MDV latency (Pratt et al, 1992) and moreover, interferon suppresses viral genome expression in the MDV latently infected lymphocytes (Volpini et al, 1995).…”

Section: Rna Extracted From Mock-infected Cells (Lane Mock) Non-oncomentioning

confidence: 99%

Significance of Marek's disease virus serotype 1‐specific phosphorylated proteins in Marek's disease skin lesions

et al. 1997

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SUMMARYSkin tissues were obtained from 12 chickens showing Marek's disease (MD) skin tumour induced by a very virulent MD/5 strain of Marek's disease virus serotype 1 (MDVl) and taken from 24 field broiler chickens (8 to 9-weeks-old) manifesting MD skin tumour. They were examined by the immunohistochemical method in order to examine the topographic expression of MDV1-specific phosphorylated proteins (PP) and by the reverse-transcription polymerase chain reaction following Southern hybridization to analyse their gene transcriptional activity. PP were massively detected and their gene transcripts were abundantly expressed only in the necrotic areas of some experimentally-induced MD cutaneous lymphoma lesions. Strong PP-positive cells were degenerate or necrotic lymphoblasts. The other field or experimentally-induced MD cutaneous lymphoma lesions, even those consisting almost completely of tumorous lymphoblasts, had only a few PP-positive lymphoid cells and few gene transcripts. Necrotic areas of feather pulp MD lymphoma lesions consisting mainly of degenerate or necrotic lymphoblasts and cytolytic feather follicle epithelium (FFE) were also strongly positive for PP. PPs and their gene transcripts were detectable only in the cytolytically infected cells such as FFE and tumorous lymphoblasts converting to the abortic state.

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“…shedding (Coppo et al, 2013a;Hughes et al, 1991;Hughes et al, 1989;Williams et al, 1992). Recent experimental studies indicate that the virus can also be detected in other organs, such as the heart, liver, spleen, lung, kidney, tongue, thymus, proventriculus, pancreas, duodenum, small intestine, large intestine, cecum, cecal tonsils, bursa, and brain (Oldoni et al, 2009;Wang et al, 2013;Zhao et al, 2013).…”

Section: Occurrence Of Infectious Laryngotracheitis Virus (Iltv) In 2mentioning

confidence: 99%

Occurrence of infectious Laryngotracheitis Virus (ILTV) in 2009-2013 in the State of São Paulo - Brazil

Parra

Nuñez

Astolfi-Ferreira

et al. 2015

Rev. Bras. Cienc. Avic.

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Infectious laryngotracheitis is a very important respiratory disease because it causes significant economic losses in the poultry industry. The target of ILTV infections is the respiratory system, and the main organ in which the virus remains latent is the trigeminal ganglia. However, the virus has demonstrated tropism for other organs as well. The present study was conducted to determine the presence of Infectious Laryngotracheitis Virus (ILTV) in the state of São Paulo. Samples submitted to LABOR-USP during the last four years (2009)(2010)(2011)(2012)(2013) analyzed by a nested/PCR technique. Out of the 682 samples from layers tested for LTIV, 12.46 % were positive, and derived from in both traditional (trachea and trigeminal ganglion) and untraditional (cecal tonsils, digestive tract and kidneys) organs utilized for ILTV diagnosis.

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Effects of certain stress factors on the re-excretion of infectious laryngotracheitis virus from latently infected carrier birds

Cited by 88 publications

References 13 publications

RFLP analysis of recent Northern Ireland isolates of infectious laryngotracheitis virus: Comparison with vaccine virus and field isolates from England, Scotland and the Republic of Ireland

RFLP analysis of recent Northern Ireland isolates of infectious laryngotracheitis virus: Comparison with vaccine virus and field isolates from England, Scotland and the Republic of Ireland

Significance of Marek's disease virus serotype 1‐specific phosphorylated proteins in Marek's disease skin lesions

Occurrence of infectious Laryngotracheitis Virus (ILTV) in 2009-2013 in the State of São Paulo - Brazil

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