Effects of Celastrus paniculatus on passive avoidance performance and biogenic amine turnover in albino rats

Celastrus paniculatus seed water soluble extracts protect against glutamate toxicity in neuronal cultures from rat forebrain

“…of mentally retarded children (Nalini et al, 1986). More recently, rats treated with CP seed oil for 15 days exhibited a significant decrease in the levels of norepinephrine, dopamine, serotonin and their respective metabolites in both brain and urine (Nalini et al, 1995). Chronic treatment with CP seed oil reversed scopolamine-induced deficits in navigational memory performance of rats (Gattu et al, 1997).…”

Herbal Remedies to Treat Anxiety Disorders

“…In another study, rats treated daily with 850 mg/kg of CP oil for 15 days exhibited a significant improvement in their retention time in a two-way passive avoidance task. CP also produced a significant decrease in the content of norepinephrine, dopamine and serotonin and certain of their respective metabolites in the brain (Nalini et al, 1995). Previous findings indicate that the aqueous extract of CP seed has cognitive-enhancing properties and an antioxidant effect might be involved (Kumar and Gupta, 2002).…”

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“…These findings demonstrate the facilitatory effect of Aeglemarmelos on learning and memory (nootropic activity). This may be attributed to the involvement of neurotransmitters like acetylcholine, serotonin, noradrenaline and dopamine, which play a vital role in the cognitive functions) 14 .…”