Effects of cardiac resynchronization therapy on echocardiographic indices, functional capacity, and clinical outcomes of patients with a systemic right ventricle

Jauvert, Gaël; Rousseau-Paziaud, Juliette; Villain, Elisabeth; Iserin, Laurence; Hidden‐Lucet, Françoise; Ladouceur, Magalie; Sidi, Daniel

doi:10.1093/europace/eun319

Cited by 77 publications

(46 citation statements)

References 16 publications

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“…Echocardiography would have revealed interventricular dyssynchrony via a measurement of the difference between the systemic and pulmonary pre-ejection intervals [13]. However, it was not useful for the evaluation in the present case because of inadequate acoustic windows due to the anterior position of the aorta and mechanical valve in the PA.…”

Section: Discussionmentioning

confidence: 84%

Interventricular dyssynchrony in a patient with a biventricular physiology and a systemic right ventricle

et al. 2016

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We describe of a unique pattern of cardiac dyssynchrony in a patient with a biventricular physiology and systemic right ventricle (RV): the interventricular dyssynchrony due to a contraction delay between the left ventricle and RV. In the present case, the cineangiography and intracardiac electrocardiography of the RV did not reveal intraventricular dyssynchrony of the RV, but revealed interventricular dyssynchrony. In addition, the pressure curves of the ventricles exhibited time phase differences between the two ventricles. The cardiac resynchronization therapy determining the pacing lead positions based on the idea of interventricular dyssynchrony induced reverse cardiac remodeling in this patient with systemic RV dysfunction.

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Section: Discussionmentioning

confidence: 84%

Interventricular dyssynchrony in a patient with a biventricular physiology and a systemic right ventricle

et al. 2016

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“…In patients with widened QRS complex (QRS duration > 120 -140 ms, sometimes > 200 ms) due to bundle branch blocks, the electromechanical dyssyn-Case Reports in Clinical Medicine chrony create insufficiency in ventricular ejection and restoration of electrical synchrony with transvenous permanent para-Hisian pacing (cardiac resynchronization therapy) reduces the QRS duration and improves the hemodynamics of the failing systemic right ventricle [45] [46], but it is technically challenging [47] Complete heart block is also a common cause of death [48]. Early pacemaker placement is recommended in the setting of complete heart block if there is RV dysfunction, symptoms of bradycardia or heart failure and urgently done if it occurs during or after the surgical intervention when the bradycardia is intolerable.…”

Section: Interventional Therapymentioning

confidence: 99%

Rheumatic “Taussig-Bing Heart”: A Case Report

Muthiah¹

2018

CRCM

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Aim: To report a case of acyanotic Taussig-Bing heart, anatomically consistent with L-transposition and rheumatic Left AV valve regurgitation associated with complete AV block in an adolescent male. Introduction: TaussigBing heart is one of the conotruncal malformation, characterized by doubleoutlet right ventricle (DORV) and a subpulmonary VSD. Embryologically, abnormal cardiac looping with malalignment of conotruncal septum result its complexity and great artery relationships. Case Report: A 14-year old acyanotic boy presented with severe left-sided AV valve regurgitation and bradycardia. ECG revealed left sided morphologic right ventricular hypertrophy (RVH) as evidenced by a loss of septal Q waves in left precordial leads suggesting ventricular inversion. X-ray chest revealed a straight upper right cardiac border due to loss of normal relationship of great vessels and cardiomegaly due to both left atrial and morphologic right ventricular enlargements suggesting a left-sided regurgitant lesion. Echocardiography revealed the ventricular inversion, primary origin of both L-transposed great arteries from the left-sided morphologic right ventricle suggesting a "double-outlet morphologic right ventricle" with "double discordance" and a subpulmonary VSD of Taussig-Bing type. The left-sided morphologic tricuspid valve is severely regurgitant due to rheumatic process resulting in heart failure which was improved with anti-failure measures and penicillin prophylaxis. Conclusion: The presence of left-sided regurgitation associated with bradycardia is a suspicion of "double discordance" and "double switch" procedure remains the mainstay of its surgical correction. Left AV valve replacement with intraventricular repair is preferred in this child since the malformation is consistent with Taussing-Bing type of DORV with L-transposition.

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“…Small series have studied indexes of atrioventricular, interventricular, and intraventricular dyssynchrony. [8][9][10][172][173][174] The benefit of CRT in the treatment of HF in a systemic RV remains unknown, although limited data suggest trends toward modest improvement in RVEF and NYHA class. Reverse RV remodeling after CRT has not yet been shown.…”

Section: Cardiac Resynchronization Therapymentioning

confidence: 99%

“…Often, a hybrid system is used that involves both transvenous and epicardial approaches. 1,4,5,[8][9][10][127][128][129][173][174][175] In ccTGA, it may be possible to implant an RV lead via the coronary sinus in individuals with suitable coronary sinus anatomy. Multiple anatomic variations have been well described and need to be understood before any attempt to place a transvenous RV lead via the coronary sinus.…”

Section: Cardiac Resynchronization Therapymentioning

confidence: 99%

Chronic Heart Failure in Congenital Heart Disease

Stout¹,

Broberg²,

Book³

et al. 2016

Circulation

287

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Effects of cardiac resynchronization therapy on echocardiographic indices, functional capacity, and clinical outcomes of patients with a systemic right ventricle

Abstract: CRT was technically feasible and associated with improvements in cardiac mechanical function and clinical status in patients with TGA, failing systemic RV, and intraventricular dyssynchrony.

Cited by 77 publications

References 16 publications

Interventricular dyssynchrony in a patient with a biventricular physiology and a systemic right ventricle

Interventricular dyssynchrony in a patient with a biventricular physiology and a systemic right ventricle

Rheumatic “Taussig-Bing Heart”: A Case Report

Chronic Heart Failure in Congenital Heart Disease

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