Effects of carboxyl and aldehyde groups on the antibacterial activity of oxidized amylose

Characterization, Antimicrobial Properties and Coatings Application of Gellan Gum Oxidized with Hydrogen Peroxide

“…Abaev et al [33] reported that the number of carboxylic groups attached to oxidized cellulosic materials was directly proportional to their antibacterial activity against S.aureus . Recently, Zi et al [34] studied the effects of aldehyde and carboxyl groups on the antibacterial activity of oxidized amylose. They concluded that the antibacterial activity of dicarboxyl-amyloses was due to the acidic pH effect produced by the carboxyl groups [29].…”

“…The OGGs with sufficient carboxyl groups can increase the proton concentration thereby decreasing the environmental pH of microorganisms. This will alter the permeability and integrity of the microbial cell membranes, and also exert some disturbance in the nutrients transport, which causes the inactivation and death of microbes [17,34,35]. This antimicrobial action does not act in a mechanism-specific manner which will lead to antibiotic-resistant strains, as many antibiotics.…”

Comparative study of antidiabetic, bactericidal, and antitumor activities of MEL@AgNPs, MEL@ZnONPs, and Ag–ZnO/MEL/GA nanocomposites prepared by using MEL and gum arabic

“…The effect of the biosynthesized nanocomposites on the morphological cells was observed using a scanning electron microscope (SEM). 36 In the current study, E. coli was selected as a model bacterium at a density of about 10 8 CFU mL À1 . E. coli treated with different samples (Ag, ZnO and GA/MEL/ZnO/Ag) and the untreated bacteria (control) were incubated at 37 C for 4 h. Aer that, the bacterial cells were collected by centrifugation (12 000 rpm, 8 min), and rinsed twice with PBS.…”

Exo⇔Endo Isomerism, MEP/DFT, XRD/HSA-Interactions of 2,5-Dimethoxybenzaldehyde: Thermal, 1BNA-Docking, Optical, and TD-DFT Studies

“…Nevertheless, improvements in density functional theory (DFT) methods have allowed the reliable theoretical application of larger molecules with even more 100 atoms in the development of new pharmaceutical agents. Therefore, DFT is currently the most powerful tool for quantum chemistry computations [7][8][9][10] and, along with X-ray single crystal analysis, has become particularly valuable for structural optimizations [9][10][11][12]. Moreover, DFT has significantly contributed in the evaluation and comparison of several experimental spectral analyses [11][12][13].…”

“…Therefore, DFT is currently the most powerful tool for quantum chemistry computations [7][8][9][10] and, along with X-ray single crystal analysis, has become particularly valuable for structural optimizations [9][10][11][12]. Moreover, DFT has significantly contributed in the evaluation and comparison of several experimental spectral analyses [11][12][13]. Molecular docking is also a suitable method for understanding the binding mode of drugs with DNA via, e.g., noncovalent interactions [14][15][16][17][18], and is usually applied for the design of novel drug structures.…”