Effects of carbaryl on the metabolism of androgens in the prostate and liver of the mouse

Dieringer, C.S.; Thomas, John A.

doi:10.1016/0013-9351(74)90039-5

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Numerous In Vitro Studies Of Receptors For All Classes Of St1

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Cited by 7 publications

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“…There are also several reports suggesting that pesticides and herbicides may bind to the androgen receptor (27)(28)(29)(30)(31)(32)(33). A variety of other compounds, not directly related to testosterone, have been shown to exert androgenic or antiandrogenic activities via binding to the androgen receptor.…”

Section: Numerous In Vitro Studies Of Receptors For All Classes Of Stmentioning

confidence: 99%

Brief Overview of Selected Aspects of Testicular Hormone Action

Bullock¹

1981

Environmental Health Perspectives

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Section: Numerous In Vitro Studies Of Receptors For All Classes Of Stmentioning

confidence: 99%

Brief Overview of Selected Aspects of Testicular Hormone Action

Bullock¹

1981

Environmental Health Perspectives

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Excretion and peripheral metabolism of 1, 2‐³H‐testosterone and androgens in rats following intoxication with organophosphorous insecticides 1 — acute exposure

Gradowska‐Olszewska

Brzeziński

Rusiecki

1984

J of Applied Toxicology

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The effects of methylbromphenvinfos (MBFV) and fenitrothion on androgen levels, excretion and peripheral metabolism were studied in male rats. The insecticides were administered orally in high, single doses. Plasma testosterone levels and urinary excretion of 11-deoxy-17-ketosteroids had increased 24 and 48 h after MBVF administration. During the same time period, fenitrothion reduced plasma and urine androgens, but after 72 h significant increases in steroid levels and excretion were apparent. Investigation of the peripheral metabolism of 3H-testosterone indicated that fenitrothion markedly diminished the urinary excretion of 3H-androstenedione during the first 48 h and then increased its level after 72 h. Simultaneously, 3H-testosterone elimination was increased during the first 24-48 h and then decreased after 72 h. These data suggest that MBFV and fenithrothion in high doses can produce significant alteration in physiological hormonal balance of the male reproductive system.

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Carbamate Insecticides

Baron

1991

Classes of Pesticides

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Effects of carbaryl on the metabolism of androgens in the prostate and liver of the mouse

Cited by 7 publications

References 8 publications

Brief Overview of Selected Aspects of Testicular Hormone Action

Brief Overview of Selected Aspects of Testicular Hormone Action

Excretion and peripheral metabolism of 1, 2‐³H‐testosterone and androgens in rats following intoxication with organophosphorous insecticides 1 — acute exposure

Carbamate Insecticides

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Effects of carbaryl on the metabolism of androgens in the prostate and liver of the mouse

Cited by 7 publications

References 8 publications

Brief Overview of Selected Aspects of Testicular Hormone Action

Brief Overview of Selected Aspects of Testicular Hormone Action

Excretion and peripheral metabolism of 1, 2‐3H‐testosterone and androgens in rats following intoxication with organophosphorous insecticides 1 — acute exposure

Carbamate Insecticides

Contact Info

Product

Resources

About

Excretion and peripheral metabolism of 1, 2‐³H‐testosterone and androgens in rats following intoxication with organophosphorous insecticides 1 — acute exposure