Effects of calorie restriction on reproductive and adrenal systems in Japanese quail: Are responses similar to mammals, particularly primates?

Ottinger, Mary Ann; Mobarak, Mohammed; Abdelnabi, Mahmoud; Roth, George S.; Proudman, J. A.; Ingram, Donald K.

doi:10.1016/j.mad.2005.03.017

Cited by 31 publications

(28 citation statements)

References 53 publications

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“…The decrease in GnIH-ir fiber immunolabeling in the POA after the beginning of the monsoon season suggests that GnIH could directly inhibit cGnRH-I cells prior to breeding, which is consistent with data on putative contact of GnIH axonal terminals with cGnRH-I and -II neurons in other passerines [Bentley et al, 2003b[Bentley et al, , 2006b and in mammals [Kriegsfeld et al, 2006]. A variety of non-photoperiodic factors may influence cGnRH-I cell activity in birds [Donoghue et al, 1989;Dunn et al, 1996;Cheng et al, 1998;Ottinger et al, 2005], however, to our knowledge this is only the second data set to demonstrate changes in cGnRH-I cell activity in a passerine that are ostensibly due to non-photoperiodic factors [Moore et al, 2006], and the first to demonstrate changes in GnIH in a free-living vertebrate.…”

Section: Discussionsupporting

confidence: 86%

Photoperiod-Independent Hypothalamic Regulation of Luteinizing Hormone Secretion in a Free-Living Sonoran Desert Bird, the Rufous-Winged Sparrow <i>(Aimophila carpalis)</i>

et al. 2007

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We investigated the regulation of luteinizing hormone (LH) in the male Rufous-winged Sparrow,Aimophila carpalis, a resident of the Sonoran desert that breeds after irregular summer rains. Although the testes develop in March due to increasing photoperiod and regress in September due to decreasing photoperiod, LH does not consistently increase in the spring as in other photoperiodic birds. However, throughout the year increased plasma LH is correlated with rainfall. To investigate this rainfall-associated regulation of LH secretion, we quantified immunocytochemical labeling for gonadotropin-releasing hormone I (GnRH-I), proGnRH (the GnRH precursor), and gonadotropin-inhibitory hormone (GnIH) in the hypothalamus of free-living adult males caught before (low LH), and during (high LH) the monsoon rainy season. Compared to pre-monsoon birds, birds caught during the monsoon season had larger immunoreactive GnRH-I (GnRH-I-ir) and proGnRH-ir cell bodies, as well as fewer, less densely labeled proGnRH-ir cell bodies. Birds caught during the monsoon had fewer, less densely labeled GnIH-ir cell bodies than birds caught before the monsoon. Further, there was no GnIH-ir labeling in the median eminence on either capture dates, suggesting that GnIH is not released to the pituitary gland via the portal vein at this time of year, but there were fewer GnIH-ir fibers in the preoptic area of birds caught during the monsoon season. Our data support the hypothesis that environmental factors associated with increased rainfall during the monsoon season stimulate GnRH synthesis and release to increase LH secretion. These data also suggest that GnIH could inhibit GnRH neuronal activity prior to the monsoon season.

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Section: Discussionsupporting

confidence: 86%

Photoperiod-Independent Hypothalamic Regulation of Luteinizing Hormone Secretion in a Free-Living Sonoran Desert Bird, the Rufous-Winged Sparrow <i>(Aimophila carpalis)</i>

et al. 2007

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“…However, avian species are an exception to this observation. Despite high metabolic rates, many birds represent long-lived species [36] . 2 The carbonyl content of proteins, which is an indicator of protein oxidation, increases exponentially as a function of age [30] .…”

Section: Experimental Evidence Of Ros and Protein Oxidation In Agingmentioning

confidence: 99%

“…Animals fed on restricted diets have been found to have lower levels of oxidized proteins [55,90] and damaged DNA [91] , a lower rate of ROS generation, lower lipid peroxidation product contents [92], and higher activities of some key enzymes, including those involved in the antioxidant defense mechanism [93,94] . Although the effects of CR on longevity of birds is not known, CR has beneficial effects on reproductive, metabolic, and physiological functions in avian species [36] .…”

Section: Cr -Effect On Protein Oxidation and Agingmentioning

confidence: 99%

Oxidative Modification of Proteins: Age-Related Changes

Chakravarti¹,

Chakravarti²

2006

Gerontology

154

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Aging is a complex biological phenomenon which involves progressive loss of different physiological functions of various tissues of living organisms. It is the inevitable fate of life and is a major risk factor for death and different pathological disorders. Based on a wide variety of studies performed in humans as well as in various animal models and microbial systems, reactive oxygen species (ROS) are believed to play a key role in the aging process. The production of ROS is influenced by cellular metabolic activities as well as environmental factors. ROS can react with all major biological macromolecules such as carbohydrates, nucleic acids, lipids, and proteins. Since, in general, proteins are the key molecules that play the ultimate role in various structural and functional aspects of living organisms, this review will focus on the age-related oxidative modifications of proteins as well as on mechanism for removal or repair of the oxidized proteins. The topics covered include protein oxidation as a marker of oxidative stress, experimental evidence indicating the role of ROS in protein oxidation, protein carbonyl content, enzymatic degradation of oxidized proteins, and effects of caloric restriction on protein oxidation in the context of aging. Finally, we will discuss different strategies which have been or can be undertaken to slow down the oxidative damage of proteins and the aging process.

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“…(2) This effect is not human specific, since sex differences in longevity occur in a huge range of animals, regardless of the absolute mean lifespan of individual species. This is true not only for mammals (3) but also for other vertebrates (such as birds (4) and fish (5) ) and for many invertebrate species. (6)(7)(8)(9) How longevity evolves is an issue that has vexed evolutionary biologists for many years.…”

Section: Introductionmentioning

confidence: 97%

Gender, immunity and the regulation of longevity

May

2007

BioEssays

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For humans and many other animals, gender is a fact of life. Most individuals are born either male or female and their sex will have an enormous influence on their behaviour, physiology and life history. In this review, I consider the effect gender has on lifespan. In particular, I discuss the role played by behaviour, immunity and oxidative damage in determining sex-dependent differences in longevity. I consider existing explanations for the effect of gender on lifespan and how these explanations fit together. Finally, I expand on the recent suggestion of a key role for the insulin/IGF-1 signalling pathway in regulating sex-dependent differences in lifespan and I highlight a number of areas for future investigation.

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Effects of calorie restriction on reproductive and adrenal systems in Japanese quail: Are responses similar to mammals, particularly primates?

Cited by 31 publications

References 53 publications

Photoperiod-Independent Hypothalamic Regulation of Luteinizing Hormone Secretion in a Free-Living Sonoran Desert Bird, the Rufous-Winged Sparrow <i>(Aimophila carpalis)</i>

Photoperiod-Independent Hypothalamic Regulation of Luteinizing Hormone Secretion in a Free-Living Sonoran Desert Bird, the Rufous-Winged Sparrow <i>(Aimophila carpalis)</i>

Oxidative Modification of Proteins: Age-Related Changes

Gender, immunity and the regulation of longevity

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