Effects of caffeine and bombesin on ethanol and food intake

Dietze, Max A.; Kulkosky, Paul J.

doi:10.1016/0024-3205(91)90239-8

Cited by 24 publications

(24 citation statements)

References 26 publications

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“…11 However, a high acute dose of caffeine (50 mg/kg, IP) decreased ethanol as well as food intake in deprived male and female rats. 167 The lack of caffeine effects on ethanol intake has been also demonstrated in a recent study. 168 The presence of caffeine (1g/L) in alcoholic solutions (10% v/v) did not increase the ethanol consumption of male rats exposed to a free-choice procedure during 50 days.…”

Section: Effect Of Caffeine On Alcohol Self-administrationmentioning

confidence: 65%

“…For instance, it has been suggested that the suppressive effects of caffeine on ethanol intake seen in some studies could be due to the use of high toxic doses of caffeine. 166,167 However, the fact that chronic caffeine blocked the ADE effect 168 suggests that caffeine could be promising as a treatment for protrective abstinence, although more studies should assess this point. [191][192][193] , and also to modulate conditioned place preference induced by methamphetamine or cocaine 6 It also would be important to study the effects of caffeine on the acquisition of Pavlovian cues associated with ethanol in this paradigm.…”

Section: Effect Of Caffeine On Alcohol Self-administrationmentioning

confidence: 99%

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The effects of adenosine antagonists on distinct aspects of motivated behavior: interaction with ethanol and dopamine depletion

Cruz¹

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Section: Effect Of Caffeine On Alcohol Self-administrationmentioning

confidence: 65%

Section: Effect Of Caffeine On Alcohol Self-administrationmentioning

confidence: 99%

The effects of adenosine antagonists on distinct aspects of motivated behavior: interaction with ethanol and dopamine depletion

Cruz¹

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“…Caffeine administered acutely did not produce a consistent pattern of effects either; a low dose of caffeine (5.0 mg/kg, IP) promoted ethanol drinking in rats using a limited-access two-bottle choice paradigm . However, a high acute dose of caffeine (50.0 mg/kg, IP) decreased ethanol as well as food intake in rats (Dietze and Kulkosky, 1991).…”

Section: Effect Of Caffeine On Alcohol Consumption: Laboratory Studiesmentioning

confidence: 91%

“…(For review see Dietze and Kulkosky, 1991). In addition, high doses of caffeine have been demonstrated to induce anxiety in humans and rodents (For a review see Correa and Font 2008).…”

Section: Effect Of Caffeine On Alcohol Withdrawalmentioning

confidence: 99%

“…However, a limited number of studies have been performed to elucidate the impact of caffeine on alcohol consumption in experimental animal models. Very few studies have been done about the impact of acute doses of caffeine on ethanol intake (Dietze and Kulkosky, 1991;. Most studies have been performed in rats using very different methodologies.…”

Section: Introcutionmentioning

confidence: 99%

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Involvement of adenosinergic and dopaminergic systems in the regulation of alcohol or sucrose intake: studies in rodent models of self-administration

Segura¹

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Effects of caffeine on alcohol reinforcement: beverage choice, self-administration, and subjective ratings

et al. 2017

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Rationale Combining alcohol and caffeine is associated with increased alcohol consumption, but no prospective experimental studies have examined whether added caffeine increases alcohol consumption. Objectives This study examined how caffeine alters alcohol self-administration and subjective reinforcing effects in healthy adults. Methods Thirty-one participants completed six double-blind alcohol self-administration sessions: three sessions with alcohol only (e.g., Beverage A) and three sessions with alcohol and caffeine (e.g., Beverage B). Participants chose which beverage to consume on a subsequent session (e.g., Beverage A or B). Effects of caffeine on overall beverage choice, number of self-administered drinks, subjective ratings (e.g., Biphasic Alcohol Effects Scale), and psychomotor performance were examined. Results A majority of participants (65%) chose to drink the alcohol beverage containing caffeine on their final self-administration session. Caffeine did not increase the number of self-administered drinks. Caffeine significantly increased stimulant effects, decreased sedative effects, and attenuated decreases in psychomotor performance attributable to alcohol. Relative to nonchoosers, caffeine choosers reported overall lower stimulant ratings, and reported greater drinking behavior prior to the study. Conclusions Although caffeine did not increase the number of self-administered drinks, most participants chose the alcohol beverage containing caffeine. Given the differences in subjective ratings and pre-existing differences in self-reported alcohol consumption for caffeine choosers and nonchoosers, these data suggest decreased stimulant effects of alcohol and heavier self-reported drinking may predict subsequent choice of combined caffeine and alcohol beverages. These predictors may identify individuals who would benefit from efforts to reduce risk behaviors associated with combining alcohol and caffeine.

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Effects of caffeine and bombesin on ethanol and food intake

Cited by 24 publications

References 26 publications

The effects of adenosine antagonists on distinct aspects of motivated behavior: interaction with ethanol and dopamine depletion

The effects of adenosine antagonists on distinct aspects of motivated behavior: interaction with ethanol and dopamine depletion

Involvement of adenosinergic and dopaminergic systems in the regulation of alcohol or sucrose intake: studies in rodent models of self-administration

Effects of caffeine on alcohol reinforcement: beverage choice, self-administration, and subjective ratings

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