Effects of cadmium on some haematological and biochemical characteristics of Oreochromis niloticus (Linnaeus, 1758) dietary supplemented with tomato paste and vitamin E

Abstract

The present study investigates the potential protective effects of tomato paste (9 mg/kg-lycopene) in comparison with vitamin E (50 mg/kg) against the impacts of cadmium (Cd) toxicity (4.64 mg/l: ¼ of 96 h LC50) on fishes Cd exposed for 15 and 30 days. Cd impacts were evaluated in terms of biological, haematological and biochemical characteristics. Cd significantly induced free radicals in serum and liver. The activities of aspartate aminotransferase and alanine aminotransferase in serum were significantly increased due to Cd. Treatment with Cd caused a significant increase in Lipid peroxidation and DNA fragmentation in liver tissue and serum glucose and total lipid. On the other hand, Cd significantly led to decline in serum total protein, blood haemoglobin, red blood cell count, haematocrit value, mean corpuscular volume, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration. Dietary supplementation with vitamin E and/or tomato paste to Cd-exposed fish declined significantly the increased lipid peroxidation and DNA fragmentation in liver tissue and the increased aspartate aminotransferase, alanine aminotransferase, glucose and total lipid in serum to the normal condition. This supplementation also significantly increased the declined serum total protein, blood haemoglobin, red blood cell count, haematocrit value, mean corpuscular volume, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration to the normal state. Cd impacts and tomato paste/or vitamin E supplementations did not reflected on the condition factor of the fish. These findings demonstrated the beneficial diet supplementation of tomato paste phytonutrients and vitamin E in counteracting the harmful effects of Cd on the characters investigated.

Physico-Chemical Characteristics and Physiological Changes in Oreochromis Niloticus From Rosetta Branch of the River Nile

“…63,64 Our findings are in agreement with these tilapia sp. collected from wadi El-Rayan and Lake Qarun.…”

Protective role of lycopene and vitamin E against diazinon-induced biochemical changes in Oreochromis niloticus

“…The present results showed that lycopene enhanced antioxidant capacity, thus protecting tissues against the DZN-induced damages, as shown by the maintenance of the TAO activity. These results suggest that vitamin E and lycopene have a protective effect on ROS as described in other studies (Mekkawy et al, 2011(Mekkawy et al, , 2013.…”

“…Diet supplementation with LYC and/or VE for 14 and 28 days showed improvement in behavioral changes and the fishes were noticed in better conditions. Similar results for vitamin E and lycopene were observed by Ohaida (2005), Mekkawy et al (2011Mekkawy et al ( , 2013, Soltan et al (2011) andUral (2013). Diazinon insecticides induce oxidative stress leading to generation of free radicals and alteration in antioxidant enzymes or oxygen free radicals scavenging enzyme (ElShenawy et al, 2010).…”

Effects of Short or Long-Term Exposure of Dithiopyr on Certaine Blood, Growth and Tissue Biochemical Parameters in Catfish (Clarias garipinus)

“…Blood glucose is a sensitive and reliable indicator of pollutants causing environmental stress in fish (Mekkawy et al, 2011). At the current study, fish exposed to acute and chronic concentrations of herbicide showed a significant increase (P<0.05) in serum glucose level during the exposure time than that of the control.…”