Effects of bone-plate materials on the healing process of fractured tibia bone under time-varying conditions: a finite element analysis

Tan, JoonHoe; Natarajan, Elango; Lim, Wei Hong; Ramesh, S.; Ang, ChunKit; Parasuraman, S.; Singh, D. Kingsly Jeba

doi:10.1088/2053-1591/ac24f8

Cited by 10 publications

(12 citation statements)

References 59 publications

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“…Kumar et al [6] also reported in their study on the application of PEEK for spine application that PEEK is a highly suitable material and alternative to titanium alloy. ese results are augmented by research conducted by Tan et al [7].…”

Section: Introductionmentioning

confidence: 86%

Extreme Gradient Boosting Regressor Solution for Defy in Drilling of Materials

Elango

Natarajan

Kaviarasan³

et al. 2022

Advances in Materials Science and Engineering

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Drilling is a quite common operation being performed in the manufacturing of components. Instrumental response in drilling is geometrical accuracy and surface integrity of the drilled parts. For the application where geometrical tolerance is very small, an operation is to be carried out very carefully. If not, rejection of drilled samples will be higher and consequently production loss will be higher. The use of prediction model in this scenario is much more appropriate and cost-effective. This research aimed to apply extreme gradient boosting (XGBoost) regressor to develop a drilling prediction model. Drilling experiments were conducted after developing design of experiments with twenty-seven unique sets. Experimental data analysis was then carried out on experimental data sets that have features such as speed, feed, angle, hole length, and surface roughness. After correlation analysis, the k-fold cross validation method was applied for parameterisation. Hyperparameters estimated from the k-fold cross validation were then applied to train and test the XGBoost regressor-based machine learning (ML) model. It is concluded from the model evaluation metric (R2) that the XGBoost regressor model has resulted 0.89 before tuning and 0.94 after tuning of the model, which is higher than the polynomial regressor and support vector regressor.

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Section: Introductionmentioning

confidence: 86%

Extreme Gradient Boosting Regressor Solution for Defy in Drilling of Materials

Elango

Natarajan

Kaviarasan³

et al. 2022

Advances in Materials Science and Engineering

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“…In addition, the in vivo evaluation revealed that the newly formed bone volume of the ternary composite was higher than that using pure PEEK. Moreover, Tan et al [ 126 ] showed that PEEK/nano-HA/short carbon fiber bioactive composite provides the most suitable implant for bone plating application for tibia. Furthermore, Zhou and Yang [ 127 ] used carbon/PEEK composite plates and demonstrated that these lower-stiffness bone plates had reduced stress shielding at the fracture site.…”

Section: Peek Bioactivitymentioning

confidence: 99%

Poly (Ether-Ether-Ketone) for Biomedical Applications: From Enhancing Bioactivity to Reinforced-Bioactive Composites—An Overview

2023

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The global orthopedic market is forecasted to reach US$79.5 billion by the end of this decade. Factors driving the increase in this market are population aging, sports injury, road traffic accidents, and overweight, which justify a growing demand for orthopedic implants. Therefore, it is of utmost importance to develop bone implants with superior mechanical and biological properties to face the demand and improve patients’ quality of life. Today, metallic implants still hold a dominant position in the global orthopedic implant market, mainly due to their superior mechanical resistance. However, their performance might be jeopardized due to the possible release of metallic debris, leading to cytotoxic effects and inflammatory responses in the body. Poly (ether-ether-ketone) (PEEK) is a biocompatible, high-performance polymer and one of the most prominent candidates to be used in manufacturing bone implants due to its similarity to the mechanical properties of bone. Unfortunately, the bioinert nature of PEEK culminates in its diminished osseointegration. Notwithstanding, PEEK’s bioactivity can be improved through surface modification techniques and by the development of bioactive composites. This paper overviews the advantages of using PEEK for manufacturing implants and addresses the most common strategies to improve the bioactivity of PEEK in order to promote enhanced biomechanical performance.

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“…Finite element analysis (FEA) is an effective tool to reveal biomechanics ( Kaku et al, 2004 ) and has been widely applied to investigate the biomechanical behavior of spine and tibia bone with good agreement with experimental measurements ( Dalstra et al, 1995 ; Anderson et al, 2008 ; Anderson et al, 2010 ). Tan et al conducted numerical study of bone healing process of a transverse fractured tibia ( Tan et al, 2021 ). Kosalishkwaran et al applied this technique to the spine, proposing an innovative method for calculating RoM ( Kosalishkwaran et al, 2019 ).…”

Section: Introductionmentioning

confidence: 99%

Role of the Anterior Center-Edge Angle on Acetabular Stress Distribution in Borderline Development Dysplastic of Hip Determined by Finite Element Analysis

Chen

Zhang

Mei

et al. 2022

Front. Bioeng. Biotechnol.

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Background: The joint with hip dysplasia is more likely to develop osteoarthritis because of the higher contact pressure, especially in the socket. The lateral center-edge angle (LCEA) is the major indicator for hip dysplasia via radiography. However, the pathological conditions of LCEA angles in the range of 18°–25° are still controversial, which challenges precise diagnosis and treatment decision-making.Objective: The purpose of this study is to investigate the influence of anterior center-edge angle (ACEA) on the mechanical stress distribution of the hip joint, via finite element analysis, to provide insights into the severity of the borderline development dysplasia.Methods: From 2017 to 2019, there were 116 patients with borderline developmental dysplasia of the hip (BDDH) enrolled in this research. Based on the inclusion criteria, nine patients were involved and categorized into three LCEA groups with the maximal ACEA differences. Patient-specific hip joint models were reconstructed from computed tomography scans, and the cartilages, including the labrum, were established via a modified numerical method. The finite element analysis was conducted to compare the stress distributions due to the different ACEA.Results: As ACEA decreased, the maximum stress of the acetabulum increased, and the high stress area developed toward the edge. Quantitative analysis showed that in the cases with lower ACEA, the area ratio of high stress increased, and the contact facies lunata area significantly affected the stress distribution.Conclusion: For patients with BDDH, both the ACEA and the area of facies lunata played essential roles in determining the severity of hip dysplasia and the mechanical mechanism preceding osteoarthritis.

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Effects of bone-plate materials on the healing process of fractured tibia bone under time-varying conditions: a finite element analysis

Cited by 10 publications

References 59 publications

Extreme Gradient Boosting Regressor Solution for Defy in Drilling of Materials

Extreme Gradient Boosting Regressor Solution for Defy in Drilling of Materials

Poly (Ether-Ether-Ketone) for Biomedical Applications: From Enhancing Bioactivity to Reinforced-Bioactive Composites—An Overview

Role of the Anterior Center-Edge Angle on Acetabular Stress Distribution in Borderline Development Dysplastic of Hip Determined by Finite Element Analysis

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