Effects of body thickness on in vivo neutron activation analysis

McNeill, K. G.; Kostalas, H.; Harrison, Joan E.

doi:10.1016/0020-708x(74)90066-0

Cited by 17 publications

(2 citation statements)

References 4 publications

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“…One can see the variation in the nitrogen counts from the largest to the smallest volunteer. It is of course appreciated that differential corrections will have to be made for the absorptions of the neutrons and y-rays in persons of different body thickness (McNeill, Kostalas andHarrison 1974, Harrison, Williams, Watts andMcNeill 1975).…”

Section: Irradiations and Resultsmentioning

confidence: 99%

In vivo determination of nitrogen using Pu-Be sources

Mernagh

Harrison

McNeil

1977

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A mehtod of measuring body nitrogen by neutron capture gamma analysis is described. The neutron flux is provided by four collimated 5 Ci Pu-Be sources, placed to give a bilateral irradiation of the subject. The 10-83 MeV thermal neutron capture gamma rays from 14N are detected by two heavily shielded 5 in X 4 in NaI(Tl) detectors. Results indicate a reproducibility +/-3% (1 SD) for a 10 min irradiation of the chest area, while giving a radiation dose equivalent of 50 mREM.

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Section: Irradiations and Resultsmentioning

confidence: 99%

In vivo determination of nitrogen using Pu-Be sources

Mernagh

Harrison

McNeil

1977

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“…Using a similar irradiation system, he found correction factors for total thickness and wax layer thickness which were close to ours. McNeill et al (1974) also studied the effect of body thickness on the efficiency of activation and measurements of calcium in the trunk. They found a reduction of calcium counts of 5% cm".…”

Section: Discussionmentioning

confidence: 99%

Total body neutron activation analysis of calcium: calibration and normalisation

Kennedy

Eastell

Ferrington

et al. 1982

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An irradiation system has been designed, using a neutron beam from a cyclotron, which optimises the uniformity of activation of calcium. Induced activity is measured in a scanning, shadow-shield whole-body counter. Calibration has been effected and reproducibility assessed with three different types of phantom. Corrections were derived for variations in body height, depth and fat thickness. The coefficient of variation for repeated measurements of an anthropomorphic phantom was 1.8% for an absorbed dose equivalent of 13 mSv (1.3 rem). Measurements of total body calcium in 40 normal adults were used to derive normalisation factors which predict the normal calcium in a subject of given size and age. The coefficient of variation of normalised calcium was 6.2% in men and 6.6% in women, with the demonstration of an annual loss of 1.5% after the menopause. The narrow range should make single measurements useful for diagnostic purposes.

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