Effects of blood flow properties on ocular hemodynamics

Mamikonyan, V. R.; Galoyan, N S; Kazaryan, E. E.; Kharlap, S I; Шмелева-Демир, О. А.; Andzhelova, D V; Rafaelyan, A. A.; Kakunina, T. A.

doi:10.17116/oftalma2015131317-21

Cited by 3 publications

(2 citation statements)

References 23 publications

(24 reference statements)

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“…CRA, central retinal artery; OCTA, optical coherence tomography angiography; BMP2 and BMP4, bone morphogenetic proteins 2 and 4; CD34 and CD55, transmembrane proteins CD34 and CD55; Flt-1, vascular endothelial growth factor receptor-1; TGF-β1, transforming growth factor beta receptor; cAMP, cyclic adenosine monophosphate; Ca 2+ , calcium; nNOS, neuronal isoform of nitric oxide; Hif-1α, hypoxia-inducible factor 1-alpha; BP, blood pressure; MAP, mean arterial pressure; OPP, ocular perfusion pressure; ChBF, choroidal blood flow. (54), altered bifurcation (55) and reduced central retinal artery (CRA) diameter and blood flow (56)(57)(58)(59). This effect appears localized to the CRA once it branches out of the ophthalmic artery (OA), and therefore affects the inner retina but not structures supplied by the OA such as eyelids, lacrimal gland, conjunctiva, posterior uveal tract or extraocular muscles.…”

Section: The Effect Of Myopia On the Retinal Vasculaturementioning

confidence: 99%

Evidence of vascular involvement in myopia: a review

Benavente-Perez

2023

Front. Med.

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The benign public perception of myopia (nearsightedness) as a visual inconvenience masks the severity of its sight-threatening consequences. Myopia is a significant risk factor for posterior pole conditions such as maculopathy, choroidal neovascularization and glaucoma, all of which have a vascular component. These associations strongly suggest that myopic eyes might experience vascular alterations prior to the development of complications. Myopic eyes are out of focus because they are larger in size, which in turn affects their overall structure and function, including those of the vascular beds. By reviewing the vascular changes that characterize myopia, this review aims to provide an understanding of the gross, cellular and molecular alterations identified at the structural and functional levels with the goal to provide an understanding of the latest evidence in the field of experimental and clinical myopia vascular research. From the evidence presented, we hypothesize that the interaction between excessive myopic eye growth and vascular alterations are tipping-points for the development of sight-threatening changes.

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Section: The Effect Of Myopia On the Retinal Vasculaturementioning

confidence: 99%

Evidence of vascular involvement in myopia: a review

Benavente-Perez

2023

Front. Med.

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“…ет большое значение, так как недостаток кровоснабжения является одним из звеньев возникновения и развития миопии [5].…”

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The Effect of Different Motor Activities at Pe Lessons on Myopia Progression

Kodaneva

Ratkina

2019

hsm

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Aim. The article deals with assessing the effect of different types of motor activity performed during physical education classes on myopia development. Materials and methods. 42 female university students aged 18 years participated in the study. All participants are characterized by acquired uncomplicated myopia. Three homogenous groups of fourteen were formed. The first group performed Nordic walking at PE classes, the second group used a fitness game (Just Dance), the third group was exempted from attending practical PE classes. All female students underwent an ophthalmic examination at the beginning and at the end of the study. The level of physical development and functional abilities of the body was established in all participants. The assessment was conducted based on the dynamics of indicators. Results. It was established that Nordic walking and lessons with a fitness game (Just Dance) did not influence significantly myopia development (р > 0.05). In the first group, myopia development was registered at the level of 0.34 diopter/year, and in the second group – 0.31 diopter/year. However, the comparison of the data obtained with those of the third group revealed a statistically significant difference (р < 0.01). Myopia development in the group exempted from attending practical PE classes was 0.75 diopter/year. Positive dynamics in motor coordination was registered in 57.1% of the first group and 64.3% of the second group. The majority of people from these groups demonstrated an increase in the indicators of the muscular strength of the leading arm and chest excursion. Moreover, more significant changes were registered for the group with a fitness game (Just Dance). The indicators of the third group remained at the same level or even worsened. Conclusion. Different types of motor activity at PE classes reduce myopia development approximately in the same way. A negative dynamics reveled for certain indicators in the third group can be probably determined by the deficit of motor activity due to huge academic load.

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Antioxidants in complex treatment of far-advanced open-angle glaucoma

2016

Vestn. oftal'mol.

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Effects of blood flow properties on ocular hemodynamics

Abstract: The use of warfarin, an indirect thrombin inhibitor, has no effect on estimated individual normal range of IOP, which is crucial for glaucoma diagnosis and monitoring.

Cited by 3 publications

References 23 publications

Evidence of vascular involvement in myopia: a review

Evidence of vascular involvement in myopia: a review

The Effect of Different Motor Activities at Pe Lessons on Myopia Progression

Antioxidants in complex treatment of far-advanced open-angle glaucoma

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