Effects of bioactive glass with and without mesoporous structures on desensitization in dentinal tubule occlusion

Chen, Wen‐Cheng; Kung, Jung-Chang; Chen, Cheng-Hwei; Hsiao, Yu‐Cheng; Shih, Chi‐Jen; Chien, Chi-Sheng

doi:10.1016/j.apsusc.2013.07.027

Cited by 22 publications

(16 citation statements)

References 23 publications

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“…BAG as one of DH treatment modelities has been studied for a long time. Ion dissolution, osteoconductivity and apatite forming ability of BAG promotes remineralization on the dentin surface through mechanically occluding dentinal tubules [2,11,13,14,17]. In some previous observations, incomplete closure of the dentinal tubule was observed.…”

Section: Discussionmentioning

confidence: 90%

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Mesoporous Bioactive Glass Combined with Graphene Oxide Quantum Dot as a New Material for a New Treatment Option for Dentin Hypersensitivity

et al. 2020

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Dentin hypersensitivity is one of the most common clinical conditions usually associated with exposed dentinal tubules. The purpose of this study was to identify the potential of a graphene oxide quantum dot coating for mesoporous bioactive glass nanoparticles as a new material for the treatment of dentin hypersensitivity by investigating its mineralization activity and dentinal tubules sealing. Mesoporous bioactive glass nanoparticle was fabricated by modified sol-gel synthesis. X-ray diffraction was performed to characterize the synthesized nanoparticle Fourier transform infra-red spectroscopy investigated the functionalized surfaces. The distribution of the specific surface area and the pore size was measure by Pore size analysis. The morphology of sample was observed by Field Emission Scanning Electron Microscope (FESEM) and Field Emission Transmission Electron Microscope (FETEM). After disk-shaped specimens of mesoporous bioactive glass nanoparticles and graphene oxide quantum dot coated mesoporous bioactive glass nanoparticles (n = 3) were soaked in the simulated body fluid for 0, 1, 5, 10,and 30 days, the amount of ions released was observed to confirm the ionic elution for mineralization. Sensitive tooth model discs (n = 20) were applied with two samples and evaluated the dentinal tubule sealing ability. The spherical mesoporous bioactive glass nanoparticles and graphene oxide quantum dot coated mesoporous bioactive glass nanoparticles with a diameter of about 500 nm were identified through FESEM and FETEM. The ion release capacity of both samples appeared to be very similar. The amount of ion released and in vitro mineralization tests confirmed that graphene oxide quantum dot coating of mesoporous bioactive glass nanoparticles did not inhibit the release of calcium, silicon and phosphate ions, but rather that graphene oxide quantum dot promoted hydroxyapatite formation. In the FESEM image of the sensitive tooth disc surface, it was observed that graphene oxide quantum dot coated mesoporous bioactive glass nanoparticles sealed tightly the dentinal tubules. The graphene oxide quantum dot coating of mesoporous bioactive glass nanoparticles not only showed the excellent dentinal sealing ability but also rapidly promoted mineralization while minimizing the size increase by coating the mesoporous bioactive glass nanoparticles.

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Section: Discussionmentioning

confidence: 90%

“…The recently introduced mesoporous bioactive glass (MBN) is found to be more effective for dentinal tubule obliteration and durability. In addition, MBN with the smaller size and larger surface area was much more effective for remineralization and dentinal tubule sealing [2,17,18].…”

Section: Introductionmentioning

confidence: 99%

Mesoporous Bioactive Glass Combined with Graphene Oxide Quantum Dot as a New Material for a New Treatment Option for Dentin Hypersensitivity

et al. 2020

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“…A proportional recoded the contrast of precipitations during the thermal cycling can provide evidence on the effect of long-term thermal cycling on the auto-mineralization mechanism. The mineralization capability of silicate-containing compounds was relatively high, and the silicate in the environment promoted mineralization with lower levels of calcium and phosphate ions [15,38,39]. Ion release was mainly attributed to the dissolution of exposed fillers.…”

Section: Mineralizing Abilitymentioning

confidence: 98%

Thermal cycling effect of dicalcium phosphate-reinforced composites on auto-mineralized dental resin

Chen

Chang

et al. 2014

Materials Science and Engineering: C

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“…Furthermore, the ions automatically released by calcium phosphate fillers may be beneficial for decalcified dentin from remineralization and controls microleakage from thermal cycling effects (Skrtic et al, 1996;Dickens-Venz et al, 2003). Although the aforementioned calcium phosphate bioceramic has the ability to induce remineralization of dentin in vitro (Thomann et al, 1990;Chen et al, 2013a), relevant studies have not supported the expected results of restorative materials against thermal cycling.…”

Section: Introductionmentioning

confidence: 95%

Thermal cycling effects on adhesion of resin–bovine enamel junction among different composite resins

Chen

Lai

et al. 2014

Journal of the Mechanical Behavior of Biomedical Materials

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Effects of bioactive glass with and without mesoporous structures on desensitization in dentinal tubule occlusion

Cited by 22 publications

References 23 publications

Mesoporous Bioactive Glass Combined with Graphene Oxide Quantum Dot as a New Material for a New Treatment Option for Dentin Hypersensitivity

Mesoporous Bioactive Glass Combined with Graphene Oxide Quantum Dot as a New Material for a New Treatment Option for Dentin Hypersensitivity

Thermal cycling effect of dicalcium phosphate-reinforced composites on auto-mineralized dental resin

Thermal cycling effects on adhesion of resin–bovine enamel junction among different composite resins

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