Effects of Bilateral Transcutaneous Tibial Nerve Stimulation on Neurogenic Detrusor Overactivity in Spinal Cord Injury: A Urodynamic Study

Kamboonlert, Kornkamon; Panyasriwanit, Sirikwan; Tantisiriwat, Natthiya; Kitisomprayoonkul, Wasuwat

doi:10.1016/j.apmr.2020.10.130

Cited by 16 publications

(12 citation statements)

References 21 publications

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“…All of the studies measured changes after a range of 2-12 weeks of treatment. Several studies were excluded due to results contaminated with non-SCI participants (25-27) and without the control group (6,(28)(29)(30)(31). Besides, one study did not provide spinal injury details, for example, the level, completeness, and SCI phase (32).…”

Section: Search Resultsmentioning

confidence: 99%

“…Neurogenic bladder in SCI is associated with multiple complications, including urinary retention and incontinence, urinary tract infections (UTIs), and potentially renal impairment with significant impact on patients' quality of life and physical health (5). Intermittent catheterization and anticholinergics are the mainstays of bladder management if the individual develops neurogenic bladder dysfunction (6). Treatment of neurogenic bladder aims to restore bladder function, preserve renal function, and prevent complications the choice of method for bladder management is guided by symptoms, renal function, and urodynamic tests.…”

Section: Introductionmentioning

confidence: 99%

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Transcutaneous Electrical Stimulation for Neurogenic Bladder Dysfunction Following Spinal Cord Injury: Meta-Analysis of Randomized Controlled Trials

Parittotokkaporn

Varghese

O’Grady

et al. 2021

Neuromodulation: Technology at the Neural Interface

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Section: Search Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Transcutaneous Electrical Stimulation for Neurogenic Bladder Dysfunction Following Spinal Cord Injury: Meta-Analysis of Randomized Controlled Trials

Parittotokkaporn

Varghese

O’Grady

et al. 2021

Neuromodulation: Technology at the Neural Interface

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“…In fact, reinitiating tibial nerve stimulation after a period of time or starting it in patients with chronic SCI is certainly a very interesting aspect that was investigated recently by Kamboonlert and colleagues. 22 They found that stimulation of patients with chronic SCI resulted in beneficial, acute effects on lower urinary tract dysfunction, opening new possibilities for this therapy.…”

Section: Discussionmentioning

confidence: 99%

Early Transcutaneous Tibial Nerve Stimulation Acutely Improves Lower Urinary Tract Function in Spinal Cord Injured Rats

Sartori

Salemi

Hofer

et al. 2022

Neurotrauma Reports

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Despite the fact that a majority of patients with an injury to the spinal cord develop lower urinary tract dysfunction, only few treatment options are available currently once the dysfunction arises. Tibial nerve stimulation has been used in pilot clinical trials, with some promising results. Hence, we investigated whether the early application of transcutaneous tibial nerve stimulation in the animal model of spinal cord injured rats can prevent the development of detrusor overactivity and/or detrusor-sphincter-dyssynergia. Rats were implanted with a bladder catheter and external urethral sphincter electromyography electrodes. A dorsal over-hemisection, resulting in an incomplete spinal cord injury at the T8/9 spinal level, induced immediate bladder paralysis. One week later, the animals received daily tibial nerve or sham stimulation for 15 days. Effects of stimulation on the lower urinary tract function were assessed by urodynamic investigation. Measurements showed improvements of several key parameters of lower urinary tract function—in particular, non-voiding bladder contractions and intravesical pressure—immediately after the completion of the stimulation period in the stimulated animals. These differences extinguished one week later, however. In the dorsal horn of the lumbosacral spinal cord, a small significant increase of the density of C-fiber afferents layers I-II was found in the stimulated animals at four weeks after spinal cord injury. Tibial nerve stimulation applied acutely after spinal cord injury in rats had an immediate beneficial effect on lower urinary tract dysfunction; however, the effect was transitory and did not last over time. To achieve more sustainable, longer lasting effects, further studies are needed looking into different stimulation protocols using optimized stimulation parameters, timing, and treatment schedules.

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“…Once the intensity is lowered to reach the sensory threshold of the treatment, they will leave it at an intensity of 0. Then, the device in sham TTNS will be switch on for 30 s at the beginning, switch off for 20 min, and switch on for 30 s before stopping [30].…”

Section: Control Group: Sham-transcutaneous Tibial Nerve Stimulationmentioning

confidence: 99%

Vibration or Transcutaneous Tibial Nerve Stimulation as a Treatment for Sexual Dysfunction in Women with Spinal Cord Injury: Study Protocol for a Randomized Clinical Trial

Díaz-Ruiz

Romero-Galisteo

Arranz-Martín

et al. 2022

IJERPH

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Background: Women with spinal cord injuries usually suffer from sexual dysfunction, such as alterations during arousal and an increase in the time to reach orgasm. However, little evidence has been found on its physiotherapeutic approach, as well as poor adherence to the latter. The aim of this study is to determine the effectiveness of two interventions to improve sexual dysfunction: the application of genital vibration and transcutaneous tibial nerve stimulation. Methods: This is a randomized clinical trial that will recruit 54 women who, one year after a spinal cord injury, suffer from sexual dysfunction associated with the latter. The participants will be randomized to three groups: (a) intervention group 1 treated with transcutaneous tibial nerve electrostimulation (n = 18), (b) intervention group 2 treated with genital vibration (n = 18), and (c) a control group (n = 18). The treatment time will be 12 weeks. Adherence to the treatment will be evaluated, as well as the effectiveness of the treatment, through the Female Sexual Function Index, the Sexual Quality of Life-Female questionnaire, quantitative sensory tests, and the improvement reported by the patient in terms of arousal and orgasm. The evaluations will be carried out before the treatment, at the end of the treatment and 3, 6 and 12 months after the end of the treatment.

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Effects of Bilateral Transcutaneous Tibial Nerve Stimulation on Neurogenic Detrusor Overactivity in Spinal Cord Injury: A Urodynamic Study

Cited by 16 publications

References 21 publications

Transcutaneous Electrical Stimulation for Neurogenic Bladder Dysfunction Following Spinal Cord Injury: Meta-Analysis of Randomized Controlled Trials

Transcutaneous Electrical Stimulation for Neurogenic Bladder Dysfunction Following Spinal Cord Injury: Meta-Analysis of Randomized Controlled Trials

Early Transcutaneous Tibial Nerve Stimulation Acutely Improves Lower Urinary Tract Function in Spinal Cord Injured Rats

Vibration or Transcutaneous Tibial Nerve Stimulation as a Treatment for Sexual Dysfunction in Women with Spinal Cord Injury: Study Protocol for a Randomized Clinical Trial

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