Effects of Beverage Solvents on Disintegration Time and Dissolution Rate of Metronidazole Tablets
J. A. Avbunudiogba,
S. E. Okafo,
C. A. Alalor
et al.
Abstract:Drug Disintegration time refers to the period within which a mechanical break-up of compressed tablet dissolve upon exposure to physiological fluids within a short period of time into tiny granules upon ingestion, while drug dissolution rate becomes a key tool in understanding the importance for its bioavailability and therapeutic effectiveness. Hence, the objective of this paper was to assess the impact of seven different solvents, which includes five non-alcoholic beverages (Exotic juice, soft drink, coffee,… Show more
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