2010
DOI: 10.3390/nu2010075
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Effects of Beta-Alanine on Muscle Carnosine and Exercise Performance: A Review of the Current Literature

Abstract: Muscle carnosine has been reported to serve as a physiological buffer, possess antioxidant properties, influence enzyme regulation, and affect sarcoplasmic reticulum calcium regulation. Beta-alanine (β-ALA) is a non-essential amino acid. β-ALA supplementation (e.g., 2-6 grams/day) has been shown to increase carnosine concentrations in skeletal muscle by 20-80%. Several studies have reported that β-ALA supplementation can increase high-intensity intermittent exercise performance and/or training adaptations. Alt… Show more

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Cited by 102 publications
(75 citation statements)
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“…Buffering capacity indicates the ability of food to resist changes in pH (Xu et al 2012). The highest pH in the 40M gnocchi sample may be attributed to inorganic phosphate, proteinbound L-histidine residues, free L-histidine or histidine-related dipeptides in meat that played a key role in buffering (Culbertson et al 2010). Gnocchi with 10% meat emulsion and 30% bean content showed a higher buffering capacity than control sample, even though there was no significant difference (p [ 0.05) between samples in terms of protein content.…”
Section: Sensory Characteristicsmentioning
confidence: 99%
“…Buffering capacity indicates the ability of food to resist changes in pH (Xu et al 2012). The highest pH in the 40M gnocchi sample may be attributed to inorganic phosphate, proteinbound L-histidine residues, free L-histidine or histidine-related dipeptides in meat that played a key role in buffering (Culbertson et al 2010). Gnocchi with 10% meat emulsion and 30% bean content showed a higher buffering capacity than control sample, even though there was no significant difference (p [ 0.05) between samples in terms of protein content.…”
Section: Sensory Characteristicsmentioning
confidence: 99%
“…Carnosine and anserine are the most abundant compounds in the non-protein nitrogen fraction of vertebrate muscle tissue (Martignoni and Winnick, 1954). The function of these dipeptides is not clearly defined; nevertheless, these molecules possess strong and specific antioxidant properties (Quinn et al, 1992), and buffering activity during physical exercise (Suzuki et al, 2006;Culbertson et al, 2010). At the same time, studies about meat have found that natural antioxidants, such as carnosine and anserine, influence the meat colour, though the mechanism by which in particular carnosine inhibits the formation of metmyoglobin from myoglobin is unclear (Kohen et al, 1988 In this study, we report data on the free amino acid content of water buffalo meat after quick extraction in ethanol followed by sulfosalicylic acid precipitation from three different Campania abattoirs without meat hanging treatment.…”
Section: Introductionmentioning
confidence: 99%
“…J Nutr Sci Vitaminol, 61, [161][162][163][164][165][166]2015 Beta-alanine (BA) is a non-essential amino acid functioning as the precursor to carnosine (1,2). BA supplementation is utilized as an ergogenic aid based on its effectiveness during exercise performance (3,4).…”
mentioning
confidence: 99%