“…However, their effects on in traventricular conduction have not been fully examined in myocardial infarction models. Previously we studied the effects of lidocaine, bepridil and SUN-1165 on intraventricular conduction in a canine model of myocardial infarction (9,10). In the present study, we in vestigated coupling interval-related effects of class I antiarrhythmic drugs, mexiletine, ciben zoline and disopyramide (1,2,(11)(12)(13), a fast, an intermediate and a slow kinetic drug (2,3,7,8), respectively, on ventricular activation in a canine model of myocardial infarction.…”