Effects of benzo(a)pyrene on early development of flatfish

Hose, Jo Ellen; Hannah, James; DiJulio, Dennis H.; Landolt, Marsha L.; Miller, Bruce S.; Iwaoka, Wayne T.; Felton, Samuel M.

doi:10.1007/bf01054893

Cited by 48 publications

(9 citation statements)

References 14 publications

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“…The data obtained in our study are in accordance with literary data concerning toxic effects of copper , oil products , and benz(a)pyrene on fish at early stages of development (Hose et al, 1982). Larvae are more sensitive to acute and long-term toxic effect of SMW, than embryos and juvenile fish.…”

Section: Resultssupporting

confidence: 90%

Dangerous Pollutants (Xenobiotics) in Urban Water Cycle

2008

NATO Science for Peace and Security Series

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Section: Resultssupporting

confidence: 90%

Dangerous Pollutants (Xenobiotics) in Urban Water Cycle

2008

NATO Science for Peace and Security Series

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“…Skeletal and cephalic abnormalities of newly hatched fish, which we encountered most frequently, are believed by some to result from genetic alterations (SchrSder, 1969(SchrSder, , 1973and Nelson, 1977), which can result from exposure to B(a)P and other polycyclic aromatic hydrocarbons. Hose et al (1981Hose et al ( , 1982 showed that developing flatfish eggs exposed to B(a)P often suffered from developmental abnormalities as did those embryos produced by females which had been exposed to B(a)P prior to egg laying.…”

Section: Teratogenesismentioning

confidence: 99%

Alterations in patterns of excretion and other metabolic functions in developing fish embryos exposed to benzo(a)pyrene

Kocan

Landolt

1984

Helgolander Meeresunters

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Steelhead trout (Salmo gairdneri) embryos were used as a model to study some of the physiological and biochemical changes which occur following exposure to sublethal levels of benzo(a)pyrene B(a)P, a known environmental contaminant. Embryos were exposed to B(a)P on day 1, 15, or 25 post fertilization, corresponding to the pre-blastula, eyed stage and late organogenesis stage of development. These times were chosen to determine whether the age of the embryo at the time of exposure influenced their response to this model compound. The changes which were observed were related to the age of the embryo at the time of exposure but not to the concentration of the B(a)P to which they were exposed. It was found that the longer the embryo developed, the more permeable the eggs became, taking up twice to 10 times as much B(a)P on day 25 as they did on day 1. Embryos exposed later in development were also able to excrete the metabolites of B(a)P through the egg membrane 10 times more rapidly than their counterparts which were exposed early during development. Following hatching, the larvae from those groups exposed later in development contained 2 to 5 times as much B(a)P bound to or dissolved in the tissues than did those exposed on day 1. Hatching time was also modified by the times of exposure, with those exposed on days 15 and 25 hatching later and over a longer period of time than either the untreated or DMSO controls. Although physical abnormalities were rare, there appeared to be a consistent increase in the level of teratogenesis in those groups which were exposed early during development.

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“…This agrees with Kiihnhold and Busch (1978), who found that following exposure of salmon eggs to Nph and Bap, most of the radioactivity was associated with the vitelline fluid and the yolk. Hose et al (1982) reported that Bap after l d of exposure accumulated primarily in the yolk-sac of sand sole eggs (Psettichthys melanostich us).…”

Section: Resultsmentioning

confidence: 99%

Uptake and elimination of aromatic hydrocarbons and a chlorinated biphenyl in eggs and larvae of cod Gadus morhua

Solbakken¹,

Tilseth²,

Palmork³

1984

Mar. Ecol. Prog. Ser.

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Artificially fertilized eggs and newly hatched larvae of cod Gadus rnorhua L. were exposed to 14C labelled naphthalene, phenanthrene, benzo(a)pyrene and 2. 4. 5. 2', 4', 5'-hexachlorobiphenyl (PCB) for 24 h and thereafter transferred to clean seawater. Radioactivity in eggs and larvae was measured at different times during exposure and after transfer to clean seawater. Maximum accumulation was found with phenanthrene, whereas naphthalene accumulated only slightly in both eggs and larvae. Naphthalene was, on the other hand, rapidly eliminated in contrast to the slow elimination of the other more lipophilic components. Most of the radioactivity accumulated in eggs was transferred to the larvae upon hatching. These findings show that cod eggs and larvae accumulate lipophilic xenobiotics from seawater and that the components will be stored for long time even after eggs and larvae are out of the polluted area.

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Effects of benzo(a)pyrene on early development of flatfish

Cited by 48 publications

References 14 publications

Dangerous Pollutants (Xenobiotics) in Urban Water Cycle

Dangerous Pollutants (Xenobiotics) in Urban Water Cycle

Alterations in patterns of excretion and other metabolic functions in developing fish embryos exposed to benzo(a)pyrene

Uptake and elimination of aromatic hydrocarbons and a chlorinated biphenyl in eggs and larvae of cod Gadus morhua

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