Effects of Aqueous Extract of Triplochiton scleroxylon on White Blood Cell Differentials in Alloxan-Induced Diabetic Rabbits

Effects of aqueous extract of Triplochiton scleroxylon on some haematological parameters and blood glucose concentrations in non-diabetic rabbits

“…However, plasma glucose concentrations observed following the administration of the extract to the test rabbits decreased significantly (P < 0.05) on the 13th and 15th days (Table 6). Diverse complications arising from the use of some orthodox drugs have grossly stimulated the exploitation of plants as possible panacea in disease management and/or cure (Bodeker, 1994;Prohp et al, 2006). This has resulted in the current increases in orthodox health care bills in most African countries including Nigeria.…”

“…This has resulted in the current increases in orthodox health care bills in most African countries including Nigeria. It is, therefore, important to promote the knowledge and understanding of the already identified herbs/plants and their specific uses in the management of various diseases (Prohp et al, 2008). The use of medicinal plants stands at advantages over orthodox medicine because these plants grow everywhere and are therefore available, accessible and affordable by all classes of people (poor and rich, rural and urban dwellers).…”

“…Blood was drawn intravenously through the large vein at the back of the ears of the rabbits in accordance with the procedure reported by Prohp et al (2006) into ethylene diamine tetra-acetic acid (EDTA) and fluoride oxalate sample tubes for haematological and glucose analyses, respectively. Prohp and Onoagbe 199 Blood glucose assay…”

“…This tree is widely distributed in tropical West Africa along waterways and farms between humid evergreen and semi deciduous forests (Prohp et al, 2008). Several preliminary studies have proved valid the claims of its hypoglycaemia and anti-diabetic properties in normal, alloxan and streptozotocin-induced diabetic rabbits (Prohp et al, 2008;Prohp and Onoagbe, 2009a, b). However, there is inadequate information in literature about the possible side effects that could arise from the use of this plant in the treatment of diabetes mellitus.…”

“…Plants are increasingly being explored and used as possible panacea for diabetes and other human diseases. Triplochiton scleroxylon is one of the medicinal plants commonly used in the rural and some urban areas in the western and southern parts of Nigeria to treat diabetes mellitus (Prohp et al, 2008;Prohp and Onoagbe, 2009a). This tree belongs to the family of African tropical medicinal plants whose active ingredients are believed to be present at the bark of the stem.…”