Effects of anti-Helicobacter pylori treatment and probiotic supplementation on intestinal microbiota

Study of Association Between Atrophic Gastritis and Body Mass Index: A Cross-Sectional Study in 10,197 Japanese Subjects

“…In the latter paper, the authors reported an increase in BMI after eradicating the infection. However, it is unclear whether the response to antibiotics was due to their effect on H. pylori infection or due to effects on the general intestinal microbiotas, which may influence BMI [40,41].…”

Real-time PCR assays for strain-specific quantification of probiotic strains in human faecal samples

“…However, in our study it seems unlikely that all the individuals in the probiotic study group would simultaneously have this other strain in faeces without consuming it, and loose it when the intervention ends. Moreover, Myllyluoma et al (2007a) analysed the same samples by plating for propionibacteria other than P. freudenreichii JS strain, and found that the amount of other propionibacteria was at constant level (approximately 3 Â 10 3 cfu per g of faeces) both in placebo and probiotic group throughout the intervention. The amount of the strain JS by plating after one week consumption of the probiotic drink was approximately 1 Â 10 7 cfu per g of faeces (Myllyluoma et al, 2005).…”

“…shermanii JS (JS; DSM 7067) and Bifidobacterium breve 99 (Bb99; DSM 13692) (see review Saxelin et al, 2010), has been shown to have beneficial effects on gastrointestinal disturbances in double-blinded, randomised, placebo-controlled long-term clinical studies. The combination was effective in the treatment of irritable bowel syndrome (Kajander, Hatakka, Poussa, Färkkilä, & Korpela, 2005); it alleviated adverse symptoms and stabilised the microbiota during Helicobacter pylori eradication treatment (Myllyluoma et al, 2005(Myllyluoma et al, , 2007a. Two strains in this probiotic combination are of human origin: L. rhamnosus GG, which has widely documented beneficial health effects (Doron, Snydman, & Gorbach, 2005), and B. breve 99 isolated from a healthy baby.…”

Probiotics and human health: Synoptic review.

“…A trial involving 120-infected patients in Italy which found that patients given the conventional medical treatments (rabeprazole, clarithromycin and amoxicillin) had a 72% successful eradication of the infection after 1 week, whereas those given the same treatment plus L. acidophilus probiotics had an 88% rate of success [37]. In another study showed that the recommended first-line H. pylori eradication therapy has detrimental acute effects as well as minor long-term effects on the intestinal microbiota [38]. They suggested that oral probiotic supplementation during and 3 weeks after triple therapy may slightly diminish the microbial disturbances, since the degree of lactobacilli/enterococci alterations decreases and the amount of total aerobes increases.…”