Abstract:Chronic obstructive pulmonary disease (COPD) is associated with patientˈs muscle mass loss and exercise intolerance. An oral supplementation with omega‐3 polyunsaturated fatty acids has been shown to increase exercise capacity in COPD patients. To understand the underlying mechanisms, we studied the effect of docosahexaenoic acid (DHA) oral administration on the muscle function of animals chronically exposed to hypoxia (FiO2 12%) for 3 weeks. Endurance time increased by 210 % in animals under Hypoxia+DHA compa… Show more
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