Effects of an Aging Population and Racial Demographics on Eye Disease Prevalence: Projections for Georgia Through 2050

Kelly, Elaine; Wen, Qing; Haddad, Danny; O’Banion, Jacquelyn

doi:10.1016/j.ajo.2019.10.028

Cited by 14 publications

(8 citation statements)

References 11 publications

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“…In addition, the incidence of fundus arteriosclerosis in males and females were 12.3% and 5.8%, respectively. The incidence of fundus arteriosclerosis was similar to many previous studies and should be of great concern [28][29][30][31] . In this study, we observed a particularly important result that there was a gender-specific association between serum uric acid and fundus arteriosclerosis, and there was a significant dose-response relationship between higher SUA levels and the incidence of fundus arteriosclerosis.…”

Section: Discussionsupporting

confidence: 88%

Gender-Specific Association between Serum Uric Acid and Incident Fundus Arteriosclerosis in Chinese Population: A Retrospective Cross-Sectional Study

Liu

Liu²,

Gao³

et al. 2020

Sci Rep

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Elevated levels of serum uric acid (SUA) were considered to be risk factors for cardiovascular disease, it has been found to be associated with increased arteriosclerosis. The aim of this study was to explore the gender specific relationship between SUA and fundus arteriosclerosis in a healthy population. In a retrospective cross-sectional study, 23474 individuals without diabetes and hypertension were included in the present study. SUA levels were cut to four groups as Q1 to Q4, according to the quartiles. The odds ratio and 95% confidence interval of different SUA levels were estimated by a binomial logistic regression model. A restrictive cubic spline method was used to estimate the dose-response relationship between SUA and fundus arteriosclerosis. Subgroup analysis was performed to find the gender-specific association between SUA and incident fundus arteriosclerosis. In males, after adjusting for confounding factors, the highest SUA level was significantly associated with the risk of incident fundus arteriosclerosis. The OR with 95%CI for Q4 was 1.44(1.18, 1.76), Q1 as a reference. Specially, for females, SUA level was not associated with the incidence of fundus arteriosclerosis. In conclusion, elevated levels of SUA were associated with the incidence of fundus arteriosclerosis in males, but not in females.

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Section: Discussionsupporting

confidence: 88%

Gender-Specific Association between Serum Uric Acid and Incident Fundus Arteriosclerosis in Chinese Population: A Retrospective Cross-Sectional Study

Liu

Liu²,

Gao³

et al. 2020

Sci Rep

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“…Similarly, Kelly et al [12] have estimated that among people aged 40 years and above, 2.2% of whites have glaucoma compared to 5.7% of blacks. Tham et al [10] have predicted that the number of people aged 40-80 years who have glaucoma will increase from 64.3 million in 2013 to 76 million by 2020, and the total prevalence of POAG was 3.54% for individuals between the age of 40 and 80 years.…”

Section: Prevalence Of Glaucomamentioning

confidence: 94%

“…In the US, Kelly et al [12] have estimated that there will be approximately 226,000 visually impaired people in the state of Georgia and about 100,000 of them would be blind by 2050. Based on a 47% increase in Georgia's population by 2050, there will be about 254,047 cases of glaucoma among people aged 40 years and above [12].…”

Section: Future Projection Of the Diseasementioning

confidence: 99%

Epidemiology of Glaucoma: The Past, Present, and Predictions for the Future

Allison

Patel

Alabi

2020

Cureus

283

197

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Glaucoma is a multifactorial optic degenerative neuropathy characterized by the loss of retinal ganglion cells. It is a combination of vascular, genetic, anatomical, and immune factors. Glaucoma poses a significant public health concern as it is the second leading cause of blindness after cataracts, and this blindness is usually irreversible. It is estimated that 57.5 million people worldwide are affected by primary open-angle glaucoma (POAG). People over 60 years of age, family members of those already diagnosed with glaucoma, steroid users, diabetics, as well as those with high myopia, hypertension, central cornea thickness of <5 mm, and eye injury are at an increased risk of glaucoma. By 2020, it is expected that approximately 76 million people will suffer from glaucoma with that number estimated to reach 111.8 million by 2040. In this article, we perform an extensive literature review focusing on the epidemiology of glaucoma and try to determine the number of people affected; we categorize them by sex, location, and level of income. Furthermore, we strive to estimate the future projection of the disease in the next 20 years (2040) while determining the disease burden, including the cost involved in treating and preventing the disease and the disease and disability projection of glaucoma.

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“…Similar to other systems, deteriorating ophthalmic function is related to age and, hence, is more prevalent in the older population [15]. When the visual field and visual acuity are compromised, they not only affect the individual's ability to see but also affect the function of other systems [9].…”

Section: Discussionmentioning

confidence: 99%

Relationship between Periodontitis and Glaucoma: A Cross-Sectional Study

Byun

Yoo

Chang

et al. 2020

Journal of Ophthalmology

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The objective of this cross-sectional study was to evaluate the association between periodontitis and glaucoma. This prospective cohort study used epidemiological data from the Korean Genome and Epidemiology Study performed between 2004 and 2016. Among 173,209 participants, 9572 patients with periodontitis and 115,332 controls (nonperiodontitis) were selected. We analysed the history of glaucoma in periodontitis and control participants. The participants were interviewed regarding their history of hypertension, diabetes mellitus, hyperlipidaemia, periodontitis, glaucoma, smoking, and alcohol consumption by trained interviewers. A logistic regression model was created to analyse the odds ratio of having a history of glaucoma among patients with periodontitis. Two-tailed analyses using chi-square and independent t-tests were used for statistical analysis. The adjusted odds ratio of periodontitis as a risk factor for glaucoma was 3.44 (95% confidence interval = 2.99–3.97, p < 0.001 ). This study demonstrated that glaucoma was associated with periodontitis.

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Effects of an Aging Population and Racial Demographics on Eye Disease Prevalence: Projections for Georgia Through 2050

Cited by 14 publications

References 11 publications

Gender-Specific Association between Serum Uric Acid and Incident Fundus Arteriosclerosis in Chinese Population: A Retrospective Cross-Sectional Study

Gender-Specific Association between Serum Uric Acid and Incident Fundus Arteriosclerosis in Chinese Population: A Retrospective Cross-Sectional Study

Epidemiology of Glaucoma: The Past, Present, and Predictions for the Future

Relationship between Periodontitis and Glaucoma: A Cross-Sectional Study

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