Effects of an Acidic Calcium Phosphate Solution and the Intraoral Fluoride-Releasing Device on Dental Caries and Fluoride Uptake in Rats

Shern, R.J.; Mirth, Dale B.; Bartkiewicz, A.; Monell-Torrens, E.; Li, S.-H.; Chow, Laurence C.

doi:10.1159/000261375

Cited by 4 publications

(2 citation statements)

References 14 publications

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“…In addition, Mirth reported a 40% reduction in occlusal fissure caries compared with the control group, a site thought not to be normally protected by fluoride. Shern et al [1991] found that the copolymer devices significantly restricted the development of carious enamel on the sulcal-morsal surfaces in rats. The only human caries study to be reported is by using the fluoride glass devices.…”

Section: Caries Studiesmentioning

confidence: 95%

Slow-Release Devices for Fluoride Delivery to High-Risk Individuals

Toumba¹

2001

Caries Res

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The latest fluoride research is investigating the use of slow-release devices for the long-term intra-oral provision of fluoride. 174 children aged 8 years with fluoride slow-releasing glass devices were shown to develop 67% fewer new carious teeth and 76% fewer new carious surfaces in a 2-year double-blind caries study. There were 55% fewer new occlusal fissure carious cavities showing that occlusal surfaces were also protected by the fluoride released from the devices. The fluoride devices release low levels of fluoride for at least 2 years and have great potential for use in preventing dental caries in high-caries-risk groups and irregular dental attenders in addition to a number of other applications.

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Section: Caries Studiesmentioning

confidence: 95%

Slow-Release Devices for Fluoride Delivery to High-Risk Individuals

Toumba¹

2001

Caries Res

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“…The most interesting finding, however, was that the occlusal surfaces were also protected in that study, since 40% fewer occlusal caries lesions were found in the test group. Another study using a similar protocol also demonstrated that the copolymer device significantly restricted the development of enamel caries on the sulcal-morsal surfaces in rats 45 .…”

Section: Effect On Caries Prevalence Reductionmentioning

confidence: 85%

Slow-release fluoride devices: a literature review

et al. 2008

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Although the prevalence of caries has decreased dramatically over the past decades, it has become a polarised disease, with most of subjects presenting low caries levels and few individuals accounting for most of the caries affected surfaces. Thus it become evident for the need of clinical approaches directed at these high-risk patients, in order to overcome problems related to compliance and low attendance at dental care centres. Slow-release fluoride devices were developed based on the inverse relationship existing between intra-oral fluoride levels and dental caries experience. The two main types of slow-release devices – copolymer membrane type and glass bead – are addressed in the present review. A substantial number of studies have demonstrated that these devices are effective in raising intra-oral F concentrations at levels able to reduce enamel solubility, resulting in a caries-protective effect. Studies in animals and humans demonstrated that the use of these devices was able to also protect the occlusal surfaces, not normally protected by conventional fluoride regimens. However, retention rates have been shown to be the main problem related to these devices and still requires further improvements. Although the results of these studies are very promising, further randomised clinical trials are needed in order to validate the use of these devices in clinical practice. The concept of continuously providing low levels of intra-oral fluoride has great potential for caries prevention in high caries-risk groups.

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Slow-release fluoride devices for the control of dental decay

Bonner¹,

Clarkson

2005

Cochrane Database of Systematic Reviews

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Background Slow-release fluoride devices have been investigated as a potentially cost-effective method of reducing dental caries in people with high risk of disease. This is the second update of the Cochrane Review first published in 2006 and previously updated in 2014. Objectives To evaluate the effectiveness and safety of different types of slow-release fluoride devices on preventing, arresting, or reversing the progression of carious lesions on all surface types of primary (deciduous) and permanent teeth.

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Effects of an Acidic Calcium Phosphate Solution and the Intraoral Fluoride-Releasing Device on Dental Caries and Fluoride Uptake in Rats

Cited by 4 publications

References 14 publications

Slow-Release Devices for Fluoride Delivery to High-Risk Individuals

Slow-Release Devices for Fluoride Delivery to High-Risk Individuals

Slow-release fluoride devices: a literature review

Slow-release fluoride devices for the control of dental decay

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