Abstract:In this in vitro study, changes in the activity of the neural membrane integral protein, ATPase, were recorded after the exposure of isolated synaptosomes to different concentrations of aluminium and lead. Both total ATPase activity and Mg2+-ATPase activity were studied. A specific mouse strain, heterozygous for a glial cell line-derived neurotrophic factor (GDNF), and the corresponding wild-type mouse cerebral tissue, were used for the synaptosome isolations. The ATPase activities of the GDNF+/– mouse synapto… Show more
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