Effects of air pollutants on upper airway disease

Jun, Young Joon; Park, Moo Kyun

doi:10.1097/aci.0000000000000235

Cited by 24 publications

(24 citation statements)

References 31 publications

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“…However, our reported overall null findings reported are in line with the literature in children where results are mixed according to the age, the window of exposure and the pollutant (Deng et al 2016;Jang et al 2016;Rancière et al 2016). It is also worthy to note that our incident rate of rhinitis may seem high at first glance.…”

Section: Discussionsupporting

confidence: 42%

“…However, there are 131 very few studies on the effect of air pollution on rhinitis (Deng et al 2016;Jang et al 2016;132 Rancière et al 2016). It has been shown that air pollution and particularly diesel exhaust 133 particles have the capability of enhancing immunological responses to allergens and elicit 134 inflammatory reactions in the airways at relatively low concentrations and even with short 135 exposure durations (Brunekreef and Sunyer 2003).…”

mentioning

confidence: 99%

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Association between air pollution and rhinitis incidence in two European cohorts

Burte

Leynaert

Bono

et al. 2018

Environment International

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Section: Discussionsupporting

confidence: 42%

mentioning

confidence: 99%

Association between air pollution and rhinitis incidence in two European cohorts

Burte

Leynaert

Bono

et al. 2018

Environment International

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“…4 The respiratory system is a primary target for key air pollutants, which can increase the risk of acute and recurrent RTIs. 6 Most of these pollutants disrupt local mucosal innate immunity mechanisms, leading to bacterial colonisation, impaired killing and increased allergen permeability.…”

Section: Introductionmentioning

confidence: 99%

Immunity‐targeted approaches to the management of chronic and recurrent upper respiratory tract disorders in children

Feleszko

Marengo

Vieira

et al. 2019

Clinical Otolaryngology

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BackgroundUpper respiratory tract infections (URTIs), including rhinitis, nasopharyngitis, tonsillitis and otitis media (OM), comprise of 88% of total respiratory infections, especially in children. Therefore effective prevention and treatment of RTIs remain a high priority worldwide. Preclinical and clinical data highlight the rationale for the use and effectiveness of immunity‐targeted approaches, including targeted immunisations and non‐specific immunomodulation in the prevention and management of recurrent upper RTIs.Objective of reviewThe idea of this review was to summarise the current evidence and address key questions concerning the use of conservative and immunity‐targeted approaches to recurrent and chronic URTIs, with a focus on the paediatric population.Search strategy/Evaluation methodLiterature searches were conducted in March 2017 and updated in September 2017 using: Academic Search Complete; CENTRAL; Health Source: Nursing/Academic Edition; MEDLINE; clinicaltrials.gov; and Cochrane databases. In total, 84 articles were retrieved and reviewed. Two independent researchers focused on primary and secondary endpoints in systematic reviews, meta‐analyses and randomised, controlled trials, using immunity‐directed strategies as the control group or within a subpopulation of larger studies. Existing guidelines and interventional/observational studies on novel applications were also included.ResultsChildren are particularly susceptible to RTIs due to the relative immaturity of their immune systems, as well as other potential predisposing factors such as day care attendance and/or toxic environmental factors (eg increased pathogenic microbial exposure and air pollutants). Recurrent URTIs can affect otherwise healthy children, leading to clinical sequelae and complications, including the development of chronic conditions or the need for surgery. Available pre‐clinical and clinical data highlight the rationale for the use and effectiveness of immunity‐targeted approaches, including targeted immunisations (flu and pneumococcal vaccines) and non‐specific immunomodulation (bacterial lysates), in the prevention and management of recurrent croup, tonsillitis, otitis media, recurrent acute rhinosinusitis and chronic rhinosinusitis.ConclusionsIn this review, we summarise the current evidence and provide data demonstrating that some immunity‐targeted strategies, including vaccination and immunomodulation, have proved effective in the treatment and prevention of recurrent and chronic URTIs in children.

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“…The condition around the research location surrounded by industry, so it can makes the air quality around it become less good. Air pollution generated by industrial activity and heavy traffic which can produce a variety of pollutants and dust that can endanger human health [6]. Based on the researcher's assumption, the existence of kitchen smoke hole in the area around the industry needs to be considered of the shape.…”

Section: H Kitchen Smoke Holementioning

confidence: 99%

“…In air pollutants there is a dangerous mixture of some particles and large amounts of gas emissions which coming from various sources of combustion, including vehicles and industries. These pollutant particles can be a risk factor for the development of respiratory diseases [6]. Epidemiological studies conducted by Fahimah et al, in Cimahi city showed a strong association between air pollutants by particulates (measures 10 microns and 2.5 microns) with respiratory diseases with a p-value of 0.002 and an OR value of 4.40 which means a children under five years living in the house with an ineligible PM 10 would be 4.40 times more risky than children under five year who lives in the house with PM 10 eligible [7].…”

mentioning

confidence: 99%

Relationship Between Particulate Matter (PM10) Concentration and House Environmental Factor with Symptoms of Acute Respiratory Infection (ARI) on Children Under Five in Rawa Terate Health Centre, Cakung Sub-district in 2017

Hayati¹,

Iriani²

2018

Proceedings of the 2nd Public Health International Conference (PHICo 2017)

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Acute Respiratory Infection (ARI) still become health problem for developing countries, especially in Indonesia. Children under five are the group with the highest incidence of ARI in Indonesia. DKI Jakarta Province is one of the provinces that have higher period prevalence of ARI than the national period prevalence. Rawa Terate village is an area where the oldest industrial area in Jakarta called Pulogadung Industrial Estate is located. Symptoms of ARI can occur due to air pollution both inside and outside the home. This study aims to determine the relationship between PM 10 concentration and house environmental factors with symptoms of ARI on children under five in Rawa Terate Health Center. The design is cross sectional with quantitative approach and conducted from July to September 2017. The number of sample in this research is 115 children under five. The results showed that the proportion of ARI symptoms in children under five was 79,1%. PM 10 concentration was significant relationship with ARI symptoms in children under five relatively (p<0,05). PM 10 is a respirable particle so it can trigger the occurrence of ARI. While for the house environmental factors such as temperature, humidity, lighting, ventilation, kitchen location, kitchen smoke hole, occupancy density and smoking family members did not show a significant relationship with ARI symptoms in children under five (p>0.05). Some of variables in this research did not comply the requirements such as PM 10 , ventilation, temperature, lighting, occupancy density and smoking family members. It is suggested to the community to improve the quality of air within the house by controlling the exchange of air inside the house by opening and closing the window at the right time, and maximizing natural lighting into the house.

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Effects of air pollutants on upper airway disease

Abstract: Traffic-derived materials and tobacco smoke are major air pollutants that aggravate upper airway disease. Novel mechanisms of action have been suggested and risk factors have been defined. However, the data are conflicting, and controlled prospective studies are required.

Cited by 24 publications

References 31 publications

Association between air pollution and rhinitis incidence in two European cohorts

Association between air pollution and rhinitis incidence in two European cohorts

Immunity‐targeted approaches to the management of chronic and recurrent upper respiratory tract disorders in children

Relationship Between Particulate Matter (PM10) Concentration and House Environmental Factor with Symptoms of Acute Respiratory Infection (ARI) on Children Under Five in Rawa Terate Health Centre, Cakung Sub-district in 2017

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