Abstract:Hypothalamic dopamine-β-hydroxylase (DBH) activity and plasma luteinizing hormone (LH) concentrations were analyzed in female C57BL/6 mice aged 2–4, 7–8, 12–13, and 16–20 months at various times of the estrous cycle. Hypothalamic DBH levels were low during diestrus and metestrus in all age groups. In animals aged 2-4, 7-8, and 12–13 months DBH activities started to rise on the evening of proestrus, and the highest levels attained at 21:00 h were significantly greater than those found during the morning (11:00 … Show more
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