Effects of aging on habituation to novelty: An ERP study

Richardson, Cassandra; Bucks, Romola S.; Hogan, Alexandra M.

doi:10.1016/j.ijpsycho.2010.09.007

Cited by 22 publications

(17 citation statements)

References 56 publications

(155 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The age-related reduction in the P3b to targets is in agreement with many reports in the literature (Anderer et al, 1998; Fabiani & Friedman, 1995; Fabiani et al, 1998; Li et al, 2013; O'Connell et al, 2012; Richardson et al, 2011) and may reflect attenuation of the categorization process or the ability to update working memory after a target has been detected (Daffner et al, 2011a; Donchin, 1981; Donchin & Coles, 1988; Knight & Scabini, 1998; Kok, 2001). Prior work has indicated that cognitive operations like sustaining attention on a task may compete for a shared pool of limited resources with the categorization/updating process (Daffner et al, 2011a).…”

Section: Discussionsupporting

confidence: 91%

“…To address this issue, we also examined age-associated differences in neural responses to targets and standards separately. A decrease in the P3b response to targets among older adults has commonly been reported (Anderer, Pascual-Marqui, Semlitsch, & Saletu, 1998; Fabiani & Friedman, 1995; Fabiani, Friedman, & Cheng, 1998; Li, Gratton, Fabiani, & Knight, 2013; O'Connell et al, 2012; Richardson, Bucks, & Hogan, 2011). Although age-associated differences in P3b responses to standard events have generally not been emphasized in the literature, we have found an increase in P3 responses to standard stimuli with age in cognitively high performing adults (Daffner et al, 2005; Riis et al, 2008).…”

Section: Introductionmentioning

confidence: 83%

See 1 more Smart Citation

Age-related decline in differentiated neural responses to rare target versus frequent standard stimuli

et al. 2014

View full text Add to dashboard Cite

One mechanism hypothesized to contribute to cognitive aging is the failure to recruit specialized neural modules and generate differentiated neural responses to various classes of stimuli. Here, ERPs were used to examine the extent to which target and standard stimulus types were processed differently by well-matched adults ages 19–99. Subjects responded to designated visual target letters under low and high load conditions. Temporospatial PCA was used to parse the P3b component, an index of categorization/memory updating. The P3b amplitude difference between targets and standards decreased substantially as a function of age. Dedifferentiation began in middle age, and continued into old-old age. The reduced differentiation of neural responses was driven by an age-related decline in the size of the P3b to targets and an age-related increase in the P3b to standards. Larger P3b amplitude to standards among older subjects was associated with higher executive capacity and better task performance. In summary, dedifferentiation begins relatively early in adulthood and progresses in a linear fashion throughout the lifespan. The age-related augmentation of the P3b to standards appears to reflect a compensatory mechanism that helps maintain task performance.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 83%

Age-related decline in differentiated neural responses to rare target versus frequent standard stimuli

et al. 2014

View full text Add to dashboard Cite

show abstract

“…As mentioned earlier, the discrepancy between our findings and those of prior studies can be accounted for by the material used. For instance, Richardson et al [46] also reported no effect on ERP latencies with repetition of computer generated novel sounds, like the ones we used here, albeit their focus was on P3 waves. Also, a previous study focusing on neural adaptation to voices did not reveal any effect on N1 and P2 latencies [64].…”

Section: Discussionmentioning

confidence: 68%

“…Some studies showed that the development of specific memory traces in the human auditory cortex is fast, taking as little as tens of seconds after repetitive stimulation [43,44,45]. In another study, Richardson et al [46] measured the P3 wave (a late positive deflection that peaks between 200 and 520 ms at parietal sites) elicited by complex, everyday sounds (e.g., dog bark, drum beat and car horn), and found a reduced P3 suppression to sound repetition in older adults compared to young adults. Their results were explained by the fact that older adults were less able to construct category templates [47].…”

Section: Discussionmentioning

confidence: 99%

Age Differences in the Neuroelectric Adaptation to Meaningful Sounds

Leung

Grady

et al. 2013

PLoS ONE

View full text Add to dashboard Cite

Much of what we know regarding the effect of stimulus repetition on neuroelectric adaptation comes from studies using artificially produced pure tones or harmonic complex sounds. Little is known about the neural processes associated with the representation of everyday sounds and how these may be affected by aging. In this study, we used real life, meaningful sounds presented at various azimuth positions and found that auditory evoked responses peaking at about 100 and 180 ms after sound onset decreased in amplitude with stimulus repetition. This neural adaptation was greater in young than in older adults and was more pronounced when the same sound was repeated at the same location. Moreover, the P2 waves showed differential patterns of domain-specific adaptation when location and identity was repeated among young adults. Background noise decreased ERP amplitudes and modulated the magnitude of repetition effects on both the N1 and P2 amplitude, and the effects were comparable in young and older adults. These findings reveal an age-related difference in the neural processes associated with adaptation to meaningful sounds, which may relate to older adults’ difficulty in ignoring task-irrelevant stimuli.

show abstract

“…According to this theory, young adults generate a novelty P3 in response to targets, but quickly habituate the response, which results in an overall diminutive P3a. There is supporting evidence that old individuals do not habituate a novelty response to novel stimuli while young adults do [19–21]. These studies employed a method in which the subject's response to novel stimuli during early blocks or trials is compared to their response during late blocks or trials in order to examine the change in the novelty response as the task progresses.…”

Section: Introductionmentioning

confidence: 99%

Does the age-related “anterior shift” of the P3 reflect an inability to habituate the novelty response?

Alperin

Mott

Holcomb

et al. 2014

Neuroscience Letters

View full text Add to dashboard Cite

Old adults often generate larger anterior neural responses than young adults when carrying out task requirements. A common finding in the ERP literature is an "anterior shift" of the P3b to targets. Utilizing principal component analysis (PCA), we recently demonstrated that rather than the P3b moving anteriorly, old adults generate a large P3a that temporally overlaps with their P3b. A dominant hypothesis for the age-related increase in anterior P3 is the failure to habituate the brain’s novelty response to rare targets. We tested this hypothesis in young and old adults by comparing the amplitude of the PCA factor representing P3a to targets presented in the first versus last of eight blocks of a visual oddball task. If, unlike young adults, old adults are unable to habituate a novelty response, one would expect 1) the P3a amplitude to decrease between the first and last blocks for young, but not old subjects and 2) the difference in P3a amplitude between young and old subjects to be greater in the last than the first block. Our results indicate the amplitude of the P3a was larger in old adults than young adults. However, this effect was not modulated by block. These findings argue against the hypothesis that an age-related increase in the P3a to targets reflects an inability of old subjects to habituate a novelty response. An alternative hypothesis is that the augmented P3a indexes the increased utilization of frontal executive functions to provide compensatory scaffolding to carry out a task.

show abstract

Effects of aging on habituation to novelty: An ERP study

Cited by 22 publications

References 56 publications

Age-related decline in differentiated neural responses to rare target versus frequent standard stimuli

Age-related decline in differentiated neural responses to rare target versus frequent standard stimuli

Age Differences in the Neuroelectric Adaptation to Meaningful Sounds

Does the age-related “anterior shift” of the P3 reflect an inability to habituate the novelty response?

Contact Info

Product

Resources

About